21 - Chromosomal Inheritance Flashcards
Sex-linked genes
a gene located on either sex chromosome. Most sex-linked genes are on the X chromosome and show distinctive patterns of inheritance; there are very few genes on the Y chromosome.
Pedigree analysis
is a diagrammatic method used to study the inheritance of traits in families. It involves creating a family tree, or pedigree chart, that displays the occurrence and appearance of phenotypes of a particular gene or trait across several generations
Chromosome inactivation
(X-chromosome inactivation), is a process that occurs in female mammals to balance the dosage of X-linked genes between males and females. Happens semi-randomly
Barr bodies
A dense object lying along the inside of the nuclear envelope in cells of female mammals, representing a highly condensed, inactivated X chromosome.
Xist gene
short for “X-inactive specific transcript,” is a crucial gene involved in the process of X-chromosome inactivation in female mammals. It is located on the X chromosome and plays a key role in silencing one of the two X chromosomes in each cell.
Wild type
the phenotype most commonly observed in natural populations; also refers to the individual with that phenotype
Mutant
a mutant refers to an organism, gene, or cell that has undergone a mutation, which is a change in its DNA sequence
Recombination
General term for the production of offspring with combinations of traits that differ from those found in either parent.
Linkage
linkage refers to the tendency of genes that are located close to each other on the same chromosome to be inherited together during meiosis, the process of forming gametes (sperm and egg cells)
Recombination frequency