16 - Transcription Flashcards

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1
Q

Transcription

A

is the synthesis (production) of RNA using information in the DNA

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2
Q

Translation

A

is the synthesis of a polypeptide using the information in the mRNA

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3
Q

Triplet

A

the genetic instructions for a polypeptide chain are written in the DNA as a series of nonoverlapping, three-nucleotide words

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4
Q

Template strand

A

1/2 DNA strands that is transcribed, it provides the pattern, or template, for the sequence of nucleotides in an RNA transcript

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5
Q

Nontemplate / coding strand

A

is the DNA strand that has the same sequence as the RNA transcript being produced, except that thymine (T) in DNA is replaced by uracil (U) in RNA.

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6
Q

Promoter

A

The DNA sequence where RNA polymerase attaches and initiates transcript

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7
Q

Transcription unit

A

the stretch of DNA downstream from the promoter that is transcribed into a RNA molecule

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8
Q

TATA box

A

is a short DNA sequence found in the promoter region of many genes in eukaryotes

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9
Q

Transcription factors

A

A collection of proteins in eukaryotes that help guide the binding of RNA polymerase and the initiation of transcription

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10
Q

RNA polymerase 2

A

is an enzyme in eukaryotic cells responsible for transcribing DNA into messenger RNA (mRNA).

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11
Q

Initiation

A

After RNA polymerase binds to the promoter, the polymerase unwinds the DNA strands and initiates RNA synthesis at the start point on the template strand

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12
Q

Elongation

A

The polymerase moves downstream, unwinding the DNA and elongating the RNA transcript 5’—-3’. After transcription has occurred, the DNA strands re-form a double helix

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13
Q

Termination

A

Eventually, the RNA transcript is released, and the polymerase detaches from the DNA

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14
Q

Uracil

A

one of the four nucleotide bases found in RNA. In DNA, uracil is replaced by thymine (T), but in RNA, uracil takes its place as a key component in the genetic code.

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15
Q

Polyadenylation signal

A

is a specific sequence of nucleotides in a gene’s DNA that signals where the addition of a poly-A tail should occur on the RNA transcript.

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16
Q

5’ Cap

A

is a modified nucleotide added to the 5’ end of a newly synthesized messenger RNA (mRNA) molecule in eukaryotic cells shortly after transcription begins.

17
Q

Poly -A tail

A

formed by an enzyme that adds 50-250 more adenine (A) nucleotides , added to the 3’ end of a newly synthesized messenger RNA (mRNA) molecule in eukaryotes

18
Q

Start codon

A

is a specific sequence of three nucleotides in mRNA that signals the beginning of protein synthesis during translation, not transcription.

19
Q

Stop codon

A
20
Q

Intron

A

non-coding segments of a gene that are transcribed into RNA but are removed during RNA processing. During RNA splicing, introns are excised, and the remaining exons are joined together to form the mature mRNA.

21
Q

Exon

A

segments of a gene that are transcribed into RNA and remain in the final messenger RNA (mRNA) after the RNA processing steps. During RNA splicing, exons are joined together, while non-coding regions called introns are removed.