08 - Cell communication Flashcards

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1
Q

Gap junction

A

a special connection between neighboring cells that allows them to communicate directly

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2
Q

Local signaling

A

Contact mediated or diffusion for a short distance

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3
Q

Long distance signaling

A

Cells communicate with each other over large distances

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4
Q

Paracrine signaling

A

is a type of cell communication where a cell produces signaling molecules that travel a short distance to affect nearby cells

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5
Q

Synaptic signaling

A

Highly specialized type of local signaling, occurs in animal nervous systems

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6
Q

Endocrine signaling

A

Specialized endocrine cells secrete hormones into bodily fluids, often blood.

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7
Q

Hormones

A

Chemicals made by glands in the body that travel through the bloodstream to send messages to other parts of the body

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8
Q

Signal transduction pathway

A

Sequence of changes in a series of different molecules

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9
Q

Signal reception

A

An epinephrine molecule
binds to a receptor on a
muscle cell.

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10
Q

signal transduction

A

Relay molecules transmit
the signal, ultimately
activating an enzyme.

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11
Q

Cellular response

A

The enzyme breaks down
glycogen, releasing glucose
that fuels the leg muscles.

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12
Q

Ligand

A

Term for a molecule that specifically binds to another molecule

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13
Q

G protein-coupled receptor (GPCR)

A

a cell - surface transmembrane receptor that works with the help of a G protein

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14
Q

Receptor tyrosine kinase (RTK)

A

Belong to a major class of plasma membrane receptors, having enzymatic activity

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15
Q

Ligand-gated ion channel

A

type of membrane channel receptor containing a region that can act as a “gate”, opening or closing the channel when the receptor changes shape

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16
Q

Intracellular receptor

A

Found in either the cytoplasm or nucleus of target cells

17
Q

Protein kinase

A

A enzyme that transfers phosphate groups from ATP to protein

18
Q

Protein phosphatase

A

Enzymes that can rapidly remove phosphate groups from proteins

19
Q

Phosphorylation

A

process where a phosphate group is added to a molecule, like a protein or sugar

20
Q

Dephosphorylaton

A

Removing of phosphate groups from proteins by enzyme

21
Q

Second messenger

A

a small molecule inside a cell that helps transmit signals from a receptor on the cell surface to target molecules inside the cell. Small, nonprotein, water-soluble molecules or ions

22
Q

Cyclic AMP (cAMP)

A

Small molecule produced from ATP

23
Q

Adenylyl cyclase

A

An enzyme embedded in plasma membrane, converts ATP to cAMP

24
Q

Epinephrine

A

(adrenaline) , a hormone and neurotransmitter produced by adrenal glands

25
Q

Protein kinase A

A

protein kinase A (PKA) is an enzyme that plays a crucial role in various cellular processes by adding phosphate groups to other proteins. PKA is like a switch operator inside the cell that helps control and regulate different cellular activities by flipping switches (phosphorylating proteins) to activate or deactivate them.

26
Q

First messenger

A

Is considered to be the extracellular signaling molecule–the ligand– that binds to the membrane receptor