18: Lymphatic System Flashcards

1
Q

What is lymph?

A

Name given to interstitial fluid once it enters the lymphatic system

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2
Q

What lymphatic structure is crucial to the small intestines ability to transport dietary lipids/lipid-soluble vitamins?

A

Lacteals, lymphatic capillaries in the small intestine

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3
Q

What is chyle?

A

A milky fluid formed in lacteals by combining dietary triglycerides and other lipids. It eventually enters the bloodstream

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4
Q

What are the 4 lymphatic structures that drain into each other, from smallest to largest?

A

Lymphatic capillaries, vessels, trunks, and ducts

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5
Q

The lymph from the upper right side of the body drains into the _______ via the __________

A

Right subclavian vein

right lymphatic duct

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6
Q

Lymph from the body (besides the upper right portion) drains into the _______ via the ________.

A

Left subclavian vein

Thoracic duct

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7
Q

The thoracis duct begins just beneath the diaphragm in the ______ that receives lymph from the lower abdomen, pelvis, and lower limbs

A

Cisterna chyli

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8
Q

Within the lymphatic system, what is the bone marrow and thymus gland? Why do they fit this category?

A

Primary lymphoid (lymphatic) organs

They are organs where lymphocytes proliferate and mature

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9
Q

What does the cortex of the thymus contain?

A

Large numbers of immature T cells

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10
Q

What does the medulla of the thymus contain?

A

T cells that are ready to be released into circulation

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11
Q

What are the secondary lymphoid (lymphatic) organs? What do they do?

A

Lymph nodes and spleen

Organs that store naive lymphocytes

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12
Q

The cortex and medulla of the lymph nodes contain large numbers of macrophages. Why?

A

Lymph nodes function to remove debris and pathogens from lymph

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13
Q

What is the difference between afferent and efferent lymphatic vessels?

A

Afferent is TOWARDS a lymph node

Efferent is AWAY from a lymph node

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14
Q

What are the two types of pulp in the spleen?

A

Red pulp (mostly RBCs)
White pulp (mostly WBCs)

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15
Q

What is the function of lymphoid nodules?

A

Screen for and attack foreign antigens by mounting the immune response

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16
Q

What are the adenoids?

A

Pharyngeal tonsils

17
Q

What is MALT? Where is it?

A

Mucosa-associated lymphoid tissue

Aggregates of lymphoid tissue directly associated with the mucous membrane epithelia (GI tract, respiratory tract, urinary tract, etc.)

18
Q

What happens in phagocytosis?

A

A phagocyte takes a pathogen in itself, essentially eating it

19
Q

What are the two major types of phagocytes?

A

Macrophage and dendritic cell

20
Q

What makes macrophages and dendritic cells “antigen presenting cells?”

A

Once they digest a pathogen, they will display certain parts of it, the antigens, on their cell membrane. The lymphocytes recognize these antigens and mount an immune response

21
Q

What are the 3 major families of lymphocytes? Where do they mature?

A

b cells, t cells, and natural killer cells

b and natural killers mature in bone marrow

t cells mature in the thymus

22
Q

What do b lymphocytes do?

A

Produce antibodies

23
Q

What do helper t cells do?

A

Function as cytokines that stimulate other immune cells

24
Q

What do cytotoxic t cells do?

A

Kill target cells by breaking apart their cell membrane

25
Q

What do regulatory t cells do?

A

Suppress other t cell immune responses

26
Q

What are memory t and memory b cells?

A

Proliferated t and b cells that stay in the body and are ready to act in case of a second, similar infection

27
Q

What are natural killer cells?

A

They are like t and b cells, but they can attack more than one type of antigen (unlike t and b)

28
Q

What is lymphoma?

A

Cancer in which masses of malignant t and/or b lymphocytes collect in lymph nodes, the spleen, liver, and other tissues.