12) Most important genes related to prolificacy in breeding

Question 1

Prolificacy

Answer 1

Producing a lot of offspring/high fertility

Question 2

List the most important genes for prolificacy in sheep and swine breeding

Answer 2

• FecB gene
• FecX gene

Question 3

FecB gene

Answer 3

• Autosomal inheritance on 6th chromosome
• Selective FHS modulator
• An extra effect in homozygotes
• Dominant and positive dose effects:
  
  • Homozygotes have higher litters

Question 4

FecB gene codes for…

Answer 4

Bone morphogenic protein receptor

BMPR-1B

Question 5

FecB gene presence in homo- and heterozygotes causes…

Answer 5

• During follicle growth + maturation
• Decreased inhibition of 17-B estradiol secretion in granulosa cells
• Leads to:
  
  • Polyovulation
  • Multiple births
  • Increased litter size

Question 6

FecX gene

Answer 6

• X-linked inheritance
• Codes for BMP-15 protein

Question 7

FecX gene effect in heterozygotes

Answer 7

• Polyovulation
• Multiple births

Question 8

FecX gene effect in homozygotes/dominant genotypes

Answer 8

• Sterile
• Infertile