10/4/22 Flashcards
Why check footwear in diabetic foot examination?
Reduced sensation can mean you can’t feel parts of your shoe that could be cutting in or hurting you.
Important to check to make sure appropriate.
Can also assess the sole so can see if any peripheral neuropathy is affecting gait
What cells are produced by myeloid and lymphoid progenitor cells?
Myeoloid
- RBC
- platelets
- granulocytes
- macrophage
- dendiritic
Lymphoid
- dendritic
- T-cells
- B-cells -> plasma cells
- NK cells
Why is the drug Phenytonin used?
Older convulsant
B12 and folate deficiency cause megaloblastic macrocytic anaemia.
What can cause normoblastic?
Alcohol
Liver disease
Hypothyroidism
What is the most common form of leukemia in adults?
CLL
How do you establish the defintive diagnosis of sickle cell anaemia?
Haemoglobin electrophoresis
What are the ferritin levels like in iron deficency anaemia?
Low
If a patient has an immune reaction to O negative blood what could this suggest they have?
Primary immunodeficency - selective IgA deficency
What is first line management for Raynauds?
CCB
What are the 3 clusters of personality disorder?
What is the management?
Cluster A - odd and ecentric
Cluster B - dramatic and unpredicitable
Cluster C - anxious and fearful
Psychotherapy and CBT - no medical intervention is indicated for personality disorder itself but may be for things like anxiety and depression that come with the condition
A = Adam Swan B = boobs are unpredictable and dramatic C = Claire
What is the first line drug that should be offered after diagnosis of a DVT?
Apixaban
Ribaroxaban
If neither suitable -> LWMH
What condition is Rouleuax formation assoc with?
Multiple myeloma
When patient presents with symptoms of thrombocytopenia (easy brusing, prolonged bleeding, heavy periods) but normal platelete count. What would you think it would be?
vWF disease
- reduced VIII - reduced clotting by reducing intrinsic pathway
What condition is assocaited with the Philadelphia chromosome?
How do you investigate and manage the condition?
CML
Investigate
- FBC and blood film
- Chromosome analysis
- Bone marrow aspirate
Treat
- if asymptomatic no speicific treatment
- chemo and radio
- splenectomy
- bone marrow transplant
How do you manage an ectopic pregnancy that has a high bCG level but no foetal heart beat?
How does this change if there is a foetal heart beat?
Methotrextae injection
Salpingectomy