1- NEOPLASIA Flashcards

1
Q

What is the definition of NEOPLASIA ?

A

is a new growth forming an abnormal mass of tissue, characterized by excessive and autonomous (uncontrolled) proliferation of cells that persists after cessation of the evoking stimuli.

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2
Q

The study of tumors is referred to as ?

A

oncology

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3
Q

Example of Tumors composed of One neoplastic cell type ?

A

1- Tumors of epithelial origin

2- Tumors of mesenchymal tissue origin

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4
Q

Give example of More than one neoplastic cell in the more than one germ cell layer ?

A

Teratoma e.g. dermoid cyst

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5
Q

Papilloma: is a benign tumor arising from ?

A

surface epithelium

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6
Q

Adenoma: is a benign tumor arising from ?

A

glandular epithelium

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7
Q

Givw example of Malignant Tumors ?

A

1- Carcinomas

2- Sarcomas

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8
Q

What is the Carcinomas ?

A

are malignant neoplasms of Epithelial cell origin.

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9
Q

What is the Sarcomas ?

A

are malignant neoplasms of Mesenchymal tissue.

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10
Q

Benign Epithelial Tumors is ?

A

1- Papilloma

2- Adenoma

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11
Q

Papilloma: is a benign tumor arising from ?

A

surface epithelium

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12
Q

Adenoma: is a benign tumor arising from ?

A

glandular epithelium

or producing gland patterns

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13
Q

Malignant Tumors is devided into ?

A

1- Carcinomas

2- Sarcomas

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14
Q

Carcinomas: are malignant neoplasms of ?

A

Epithelial cell origin.

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15
Q

Sarcomas: are malignant neoplasms of ?

A

Mesenchymal tissue

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16
Q

What is TERATOMA?

A

Teratoma is a tumor of germ-cell origin (Totipotential cells) containing structures derived from all three germ cell layers: ectoderm, mesoderm & endoderm.

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17
Q

What is the site of TERATOMA ?

A

Ovary and testis

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18
Q

What is the Definition of EMBRYONIC TUMORS ?

A

Malignant tumors derived from embryonic cell remnants

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19
Q

What is the Definition of HAMARTOMA ?

A

tumor-like developmental malformation formed of noncapsulated mass of disorganized mature tissues of the affected organ.

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20
Q

Give examples of HAMARTOMA ?

A

1- Hamartoma of Lung
2- Angiomas
3- Melanocytic Nevi

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21
Q

What is the Definition of Choristoma (Heterotopia or Heterotopic Rest) ?

A

small area of normal cells or tissues misplaced in another organ

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22
Q

Papillomas are classically ?

A

exophytic

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23
Q

PAPILLOMA is composed of ?

A

1- Simple or branching fibrovasular core

2- covered by proliferated epithelial cells

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24
Q

Papillomas are ?

A

Noncapsulated

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25
What is the Definition of Sqamous Cell Papilloma ?
Benign tumor of stratified squamous epithelium
26
What is the Definition of Transitional Cell Papilloma ?
Benign tumor arising from transitional epithelium of urinary tract
27
What is the Definition of Columnar Cell Papilloma or duct papilloma ?
Benign tumor arising from the epithelium of major ducts
28
Give exmple of Columnar Cell Papilloma ?
Duct Papilloma
29
What is the site of Sqamous Cell Papilloma ?
Skin
30
What is the site of Transitional Cell Papilloma ?
urinary bladder
31
What is the site of Columnar Cell Papilloma ?
breast
32
What is the Definition of ADENOMA ?
Benign tumor arising from glandular epithelium or forming glandular patterns
33
What is the sites of ADENOMA ?
1- Exocrine or endocrine glands | 2- Mucosal glands of GIT
34
What is the Types of ADENOMA ?
1- Simple adenoma ( e.g. thyroid adenoma ) 2- Fibroadenoma ( fibroblastic stroma + epithelial ducts in breast ) 3- Cystadenoma ( e.g. cystadenoma of ovary ) 4- Papillary Cystadenoma ( e.g. papillary cystadenoma of ovary ) 5- Adenomatous Polyp ( colon polyp)
35
What is the CONNECTIVE TISSUE TUMORS ?
``` 1- LIPOMA 2- FIBROMA 3- CHONDROMA 4- OSTEOMA 5- MYXOMA ```
36
LIPOMA: Benign tumor of ?
Adipose tissue
37
What is the site of LIPOMA ?
Subcutaneous tissue
38
What is the Gross of LIPOMA ?
capsulated, soft, yellowish mass
39
What is the Mic of LIPOMA ?
mature fat cells
40
What is the FIBROMA ?
Benign tumor of fibrous tissue (Fibroblasts)
41
What is the CHONDROMA ?
Benign tumor of cartilage
42
What is the OSTEOMA ?
Benign tumor arising in bone.
43
What is the MYXOMA ?
rare benign tumor arising from remnants of primitive mesenchyme.
44
What is the BENIGN TUMORS OF MUSCLES (MYOMAS) ?
1- LEIOMYOMA | 2- RHABDOMYOMA
45
What is the Definition of LEIOMYOMA ?
Benign tumor of smooth muscle.
46
What is the Sites of LEIOMYOMA ?
Uterus
47
What is the Gross of LEIOMYOMA ?
Uncapsulated but surrounded by False capsule
48
In the LEIOMYOMA the cut section usually shows a ?
whorly appearance.
49
Whatvp is the Definition of RHABDOMYOMA ?
An extremely rare benign tumor of striated muscles.
50
LEIOMYOMA in the Some are embedded within the myometrium is ?
intramural or interstitial
51
LEIOMYOMA in others may lie directly beneath the endometrium is ?
submucosal
52
LEIOMYOMA in the Lie directly beneath the serosa ?
subserosal
53
What is the Definition of RHABDOMYOMA ?
An extremely rare benign tumor of striated muscles.
54
What is the BENIGN TUMORS OF VESSELS (ANGIOMAS) ?
1- HEMANGIOMA | 2- LYMPHANGIOMA
55
What is the Definition of HEMANGIOMA ?
Benign tumor (or tumor-like lesion) of blood vessels.
56
What is the Definition of LYMPHANGIOMA ?
Benign tumor (or tumor-like lesion) of lymphatic vessels.
57
What is the types of HEMANGIOMA ?
1- Capillary Hemangioma | 2- Cavernous Hemangioma
58
Small vascular spaces lined by endothelium contain blood ?
Capillary Hemangioma
59
Wide vascular spaces lined by endothelium contain blood ?
Cavernous Hemangioma
60
What is the Definition of MALIGNANT EPITHELIAL TUMORS (CARCINOMA) ?
Carcinoma is a malignant tumor of epithelial cell origin
61
What is the Definition of SQUAMOUS CELL CARCINOMA ?
Malignant tumor of stratified squamous epithelium.