1- NEOPLASIA Flashcards

1
Q

What is the definition of NEOPLASIA ?

A

is a new growth forming an abnormal mass of tissue, characterized by excessive and autonomous (uncontrolled) proliferation of cells that persists after cessation of the evoking stimuli.

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2
Q

The study of tumors is referred to as ?

A

oncology

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3
Q

Example of Tumors composed of One neoplastic cell type ?

A

1- Tumors of epithelial origin

2- Tumors of mesenchymal tissue origin

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4
Q

Give example of More than one neoplastic cell in the more than one germ cell layer ?

A

Teratoma e.g. dermoid cyst

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5
Q

Papilloma: is a benign tumor arising from ?

A

surface epithelium

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6
Q

Adenoma: is a benign tumor arising from ?

A

glandular epithelium

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7
Q

Givw example of Malignant Tumors ?

A

1- Carcinomas

2- Sarcomas

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8
Q

What is the Carcinomas ?

A

are malignant neoplasms of Epithelial cell origin.

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9
Q

What is the Sarcomas ?

A

are malignant neoplasms of Mesenchymal tissue.

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10
Q

Benign Epithelial Tumors is ?

A

1- Papilloma

2- Adenoma

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11
Q

Papilloma: is a benign tumor arising from ?

A

surface epithelium

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12
Q

Adenoma: is a benign tumor arising from ?

A

glandular epithelium

or producing gland patterns

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13
Q

Malignant Tumors is devided into ?

A

1- Carcinomas

2- Sarcomas

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14
Q

Carcinomas: are malignant neoplasms of ?

A

Epithelial cell origin.

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15
Q

Sarcomas: are malignant neoplasms of ?

A

Mesenchymal tissue

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16
Q

What is TERATOMA?

A

Teratoma is a tumor of germ-cell origin (Totipotential cells) containing structures derived from all three germ cell layers: ectoderm, mesoderm & endoderm.

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17
Q

What is the site of TERATOMA ?

A

Ovary and testis

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18
Q

What is the Definition of EMBRYONIC TUMORS ?

A

Malignant tumors derived from embryonic cell remnants

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19
Q

What is the Definition of HAMARTOMA ?

A

tumor-like developmental malformation formed of noncapsulated mass of disorganized mature tissues of the affected organ.

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20
Q

Give examples of HAMARTOMA ?

A

1- Hamartoma of Lung
2- Angiomas
3- Melanocytic Nevi

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21
Q

What is the Definition of Choristoma (Heterotopia or Heterotopic Rest) ?

A

small area of normal cells or tissues misplaced in another organ

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22
Q

Papillomas are classically ?

A

exophytic

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23
Q

PAPILLOMA is composed of ?

A

1- Simple or branching fibrovasular core

2- covered by proliferated epithelial cells

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24
Q

Papillomas are ?

A

Noncapsulated

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25
Q

What is the Definition of Sqamous Cell Papilloma ?

A

Benign tumor of stratified squamous epithelium

26
Q

What is the Definition of Transitional Cell Papilloma ?

A

Benign tumor arising from transitional epithelium of urinary tract

27
Q

What is the Definition of Columnar Cell Papilloma or duct papilloma ?

A

Benign tumor arising from the epithelium of major ducts

28
Q

Give exmple of Columnar Cell Papilloma ?

A

Duct Papilloma

29
Q

What is the site of Sqamous Cell Papilloma ?

A

Skin

30
Q

What is the site of Transitional Cell Papilloma ?

A

urinary bladder

31
Q

What is the site of Columnar Cell Papilloma ?

A

breast

32
Q

What is the Definition of ADENOMA ?

A

Benign tumor arising from glandular epithelium or forming glandular patterns

33
Q

What is the sites of ADENOMA ?

A

1- Exocrine or endocrine glands

2- Mucosal glands of GIT

34
Q

What is the Types of ADENOMA ?

A

1- Simple adenoma ( e.g. thyroid adenoma )
2- Fibroadenoma ( fibroblastic stroma + epithelial ducts in breast )
3- Cystadenoma ( e.g. cystadenoma of ovary )
4- Papillary Cystadenoma ( e.g. papillary cystadenoma of ovary )
5- Adenomatous Polyp ( colon polyp)

35
Q

What is the CONNECTIVE TISSUE TUMORS ?

A
1- LIPOMA
2- FIBROMA
3- CHONDROMA
4- OSTEOMA
5- MYXOMA
36
Q

LIPOMA: Benign tumor of ?

A

Adipose tissue

37
Q

What is the site of LIPOMA ?

A

Subcutaneous tissue

38
Q

What is the Gross of LIPOMA ?

A

capsulated, soft, yellowish mass

39
Q

What is the Mic of LIPOMA ?

A

mature fat cells

40
Q

What is the FIBROMA ?

A

Benign tumor of fibrous tissue (Fibroblasts)

41
Q

What is the CHONDROMA ?

A

Benign tumor of cartilage

42
Q

What is the OSTEOMA ?

A

Benign tumor arising in bone.

43
Q

What is the MYXOMA ?

A

rare benign tumor arising from remnants of primitive mesenchyme.

44
Q

What is the BENIGN TUMORS OF MUSCLES (MYOMAS) ?

A

1- LEIOMYOMA

2- RHABDOMYOMA

45
Q

What is the Definition of LEIOMYOMA ?

A

Benign tumor of smooth muscle.

46
Q

What is the Sites of LEIOMYOMA ?

A

Uterus

47
Q

What is the Gross of LEIOMYOMA ?

A

Uncapsulated but surrounded by False capsule

48
Q

In the LEIOMYOMA the cut section usually shows a ?

A

whorly appearance.

49
Q

Whatvp is the Definition of RHABDOMYOMA ?

A

An extremely rare benign tumor of striated muscles.

50
Q

LEIOMYOMA in the Some are embedded within the myometrium is ?

A

intramural or interstitial

51
Q

LEIOMYOMA in others may lie directly beneath the endometrium is ?

A

submucosal

52
Q

LEIOMYOMA in the Lie directly beneath the serosa ?

A

subserosal

53
Q

What is the Definition of RHABDOMYOMA ?

A

An extremely rare benign tumor of striated muscles.

54
Q

What is the BENIGN TUMORS OF VESSELS (ANGIOMAS) ?

A

1- HEMANGIOMA

2- LYMPHANGIOMA

55
Q

What is the Definition of HEMANGIOMA ?

A

Benign tumor (or tumor-like lesion) of blood vessels.

56
Q

What is the Definition of LYMPHANGIOMA ?

A

Benign tumor (or tumor-like lesion) of lymphatic vessels.

57
Q

What is the types of HEMANGIOMA ?

A

1- Capillary Hemangioma

2- Cavernous Hemangioma

58
Q

Small vascular spaces lined by endothelium contain blood ?

A

Capillary Hemangioma

59
Q

Wide vascular spaces lined by endothelium contain blood ?

A

Cavernous Hemangioma

60
Q

What is the Definition of MALIGNANT EPITHELIAL TUMORS (CARCINOMA) ?

A

Carcinoma is a malignant tumor of epithelial cell origin

61
Q

What is the Definition of SQUAMOUS CELL CARCINOMA ?

A

Malignant tumor of stratified squamous epithelium.