Zofran (Ondansetron) Flashcards
0
Q
Action
A
Blocks serotonin at 5-HT3 receptor sites in Vagal nerve terminals
1
Q
Class (2)
A
- Antiemetic
- Serotonin type 3 (5-HT3) agonist
2
Q
Indication
A
Prevent nausea and vomiting
3
Q
Dose/Route
A
- 4 mg IV (repeat if no effect in 5 min)
- Onset: rapid
- Peak: 15-30 min
- Duration: 4-8 hr
4
Q
Peds Dose
A
0.1 mg/kg IV
5
Q
Standard Prep
A
4 mg/2 ml
6
Q
Contraindication
A
Hypersensitivity
7
Q
Side Effects (8)
A
- Hypotension
- Bradycardia
- Blurred vision
- Bronchospasm
- Urinary retention
- Constipation/diarrhea
- Anxiety
- Dizziness
8
Q
Precaution
A
Use in caution in people with hepatic insufficiency
