Pralidoxime (Protopam Chloride/2-Pam Chloride) Flashcards

1
Q

Class

A

Cholinesterase reactivator

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2
Q

Action

A

Reactivates the enzyme Acetylcholinesterase, which allows ACH to be degraded, thus relieving the parasympathetic overstimulation caused by excess ACH

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3
Q

Indication (2)

A
  • Nerve agent exposure with sx of pinpoint pupils, runny nose, SOB
  • Organophosphate poisoning (after atropine)
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4
Q

Contraindications

A

Hypersensitivity

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5
Q

Side Effects (6)

A
  • Tachycardia
  • HTN
  • Laryngospasm
  • Hyperventilation
  • Muscle weakness
  • Nausea
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