Pralidoxime (Protopam Chloride/2-Pam Chloride) Flashcards
1
Q
Class
A
Cholinesterase reactivator
2
Q
Action
A
Reactivates the enzyme Acetylcholinesterase, which allows ACH to be degraded, thus relieving the parasympathetic overstimulation caused by excess ACH
3
Q
Indication (2)
A
- Nerve agent exposure with sx of pinpoint pupils, runny nose, SOB
- Organophosphate poisoning (after atropine)
4
Q
Contraindications
A
Hypersensitivity
5
Q
Side Effects (6)
A
- Tachycardia
- HTN
- Laryngospasm
- Hyperventilation
- Muscle weakness
- Nausea