Verapamil (Isoptin/Calan)

Question 1

Class

Answer 1

Calcium channel blocker

Question 2

Actions (5)

Answer 2

• Reduces myocardial O2 demand through its negative inotropic & chronotropic effects
• Slows conduction and prolongs refractoriness in the AV node by blocking calcium at the slow channels
• Decreases automaticity of all pacemaker cells
• Increases coronary blood flow by decreasing coronary spasm
• Relaxes vascular smooth muscle which decreases systemic vascular resistance

Question 3

Indications (3)

Answer 3

• Narrow complex PSVT’s
• HTN
• Post-infarction angina

Question 4

Contraindications (6)

Answer 4

• Hypotension
• Conduction defects > 1st degree AV block
• Pt taking beta blockers
• WPW with Afib or flutter (ventricular rate may accelerate)
• Wide complex tachycardias of unknown origin
• CHF

Question 5

Side Effects (5)

Answer 5

• Hypotension
• Bradyarrhythmias
• CHF
• N/V
• Complete AV block