Wound, bone, & joint infection Flashcards

1
Q

A 74 year old patient presents with a 3 hour history of sudden onset, intense pain in the right knee and a fever. Rank the following diagnoses given this information, with the most likely diagnosis given first.

Reactive arthritis

Rheumatoid arthritis

Septic arthritis

Osteoarthritis

Patellar tendonitis

A
Septic arthritis
Reactive arthritis
Rheumatoid arthritis
Patellar tendonitis
Osteoarthritis
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2
Q

Choose the most appropriate answer from the list

  • Septic Arthritis
  • Acute osteomyelitis
  • Prosthetic Joint Infection
  • Chronic osteomyelitis
  • Haematogenous osteomyelitis
  • Brodie’s abscess
  • Vertebral osteomyelitis
  • Cellulitis
  • Spinal cord neoplasm
  • Gout

60 year old diabetic patient presents with localized back pain, fever, malaise and swelling at the site of pain. Rasised CRP.

A

Vertebral osteomyelitis

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3
Q

Choose the most appropriate answer from the list

  • Septic Arthritis
  • Acute osteomyelitis
  • Prosthetic Joint Infection
  • Chronic osteomyelitis
  • Haematogenous osteomyelitis
  • Brodie’s abscess
  • Vertebral osteomyelitis
  • Cellulitis
  • Spinal cord neoplasm
  • Gout

29 year old patient presents with 1 week history of painful, red, swollen restricted knee joint. Raised CRP. High WCC (>50,000 WCC cells/mm3). Causative agent is Staphyloccus aureus. Patient is an i.v. drug abuser.

A

Septic Arthritis

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4
Q

Choose the most appropriate answer from the list

  • Septic Arthritis
  • Acute osteomyelitis
  • Prosthetic Joint Infection
  • Chronic osteomyelitis
  • Haematogenous osteomyelitis
  • Brodie’s abscess
  • Vertebral osteomyelitis
  • Cellulitis
  • Spinal cord neoplasm
  • Gout

Young patient presents with sudden fever, bone pain, swelling, restricted movement in elbow joint 3 weeks after injury.

A

Acute osteomyelitis

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5
Q

Choose the most appropriate answer from the list

  • Septic Arthritis
  • Acute osteomyelitis
  • Prosthetic Joint Infection
  • Chronic osteomyelitis
  • Haematogenous osteomyelitis
  • Brodie’s abscess
  • Vertebral osteomyelitis
  • Cellulitis
  • Spinal cord neoplasm
  • Gout

Patient presents 1 month after bilateral arthoplasty. Claims the joints haven’t “felt right”. Fever, leaking wounds, pain. Staphyloccus aureus was isolated.

A

Prosthetic Joint Infection

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6
Q

Choose the most appropriate answer from the list

  • Septic Arthritis
  • Acute osteomyelitis
  • Prosthetic Joint Infection
  • Chronic osteomyelitis
  • Haematogenous osteomyelitis
  • Brodie’s abscess
  • Vertebral osteomyelitis
  • Cellulitis
  • Spinal cord neoplasm
  • Gout

Sudden onset of excruciating pain in left MTP joint. Swelling and inflammation. High uric acid.

A

Gout

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7
Q

Choose the most appropriate answer from the list

  • Blood culture and synovial fluid aspirate
  • Open biopsy of the joint
  • Chronic Osteomyelitis
  • Plain X-Ray
  • CT
  • PO Flucloxacillin
  • Enterobacter
  • Prosthetic Joint Infection
  • Infected Baker’s cyst
  • Septic Arthritis
  • IV Gentamycin
  • Staph. Aureus
  • MRI
  • Strep Pyogenes
  • Neisseria Meningitides
  • Vertebral Osteomyelitis

A 48yo lady with a BMI of 28 presents to your rapid access clinic with a 3 week history of a painful L knee. On examination, you note the joint is oedematous and hot. She is pyrexial, has a reduced range of movement and feels generally lethargic. Upon further questioning, she reports having intra-articular steroid injections for her Rheumatoid Arthritis a month previously but otherwise she has no medical problems. What is your working diagnosis?

What should you do nex?

A

Septic Arthritis

Blood culture and synovial fluid aspirate

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8
Q

Choose the most appropriate answer from the list

  • Blood culture and synovial fluid aspirate
  • Open biopsy of the joint
  • Chronic Osteomyelitis
  • Plain X-Ray
  • CT
  • PO Flucloxacillin
  • Enterobacter
  • Prosthetic Joint Infection
  • Infected Baker’s cyst
  • Septic Arthritis
  • IV Gentamycin
  • Staph. Aureus
  • MRI
  • Strep Pyogenes
  • Neisseria Meningitides
  • Vertebral Osteomyelitis

A 69yo man is recovering on the surgical ward after surgery for L2/3 vertebral disc herniation and spinal canal compression. The operation went well but now he has spiked a temperature and is complaining of a ‘bad back’ and a pain in his leg. What diagnostic test is most sensitive in helping your diagnosis?

What causative organism do you suspect?

A

MRI

Staph. Aureus

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9
Q

Choose the most appropriate answer from the list

  • Blood culture and synovial fluid aspirate
  • Open biopsy of the joint
  • Chronic Osteomyelitis
  • Plain X-Ray
  • CT
  • PO Flucloxacillin
  • Enterobacter
  • Prosthetic Joint Infection
  • Infected Baker’s cyst
  • Septic Arthritis
  • IV Gentamycin
  • Staph. Aureus
  • MRI
  • Strep Pyogenes
  • Neisseria Meningitides
  • Vertebral Osteomyelitis

An 81yo Lady with Type 1 DM and a BMI of 26 presents to you in A&E, four weeks post bilateral hip replacement surgery. She is in pain, is not yet mobilising and is complaining that her hips have ‘never felt right’ since the surgery. Initial blood tests show Hb 140g/L, WCC 20x109/L, CRP 156, Plt 267, Na 134mmol/L, K 4.8mmol/L. Pelvic x-ray shows areas of lysis around the acetabular component of both joints and joint aspirate reveals 6700 WCC/ml. What do you suspect in this lady?

A

Prosthetic Joint Infection

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10
Q

Choose the most appropriate answer from the list

  • Staphylococcus aureus
  • Borrelia burgdorferi
  • Escherichia coli
  • Brucella abortus
  • Pseudomonas aeruginosa
  • Mycobacterium tuberculosis
  • Kingella kingae
  • Streptococcus pyogenes
  • Coagulase negative staph
  • Proteus mirabilis
  • Haemophilus influenza
  • Candida albicans
  • Neisseria gonorrhoeae
  • Bartonella henselae
  • Salmonella
  • Toxoplasma gondii

Most common causative organism in septic arthritis

A

Staphylococcus aureus

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11
Q

Choose the most appropriate answer from the list

  • Staphylococcus aureus
  • Borrelia burgdorferi
  • Escherichia coli
  • Brucella abortus
  • Pseudomonas aeruginosa
  • Mycobacterium tuberculosis
  • Kingella kingae
  • Streptococcus pyogenes
  • Coagulase negative staph
  • Proteus mirabilis
  • Haemophilus influenza
  • Candida albicans
  • Neisseria gonorrhoeae
  • Bartonella henselae
  • Salmonella
  • Toxoplasma gondii

Causes arthritis mainly in young children

A

Haemophilus influenza

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12
Q

Choose the most appropriate answer from the list

  • Staphylococcus aureus
  • Borrelia burgdorferi
  • Escherichia coli
  • Brucella abortus
  • Pseudomonas aeruginosa
  • Mycobacterium tuberculosis
  • Kingella kingae
  • Streptococcus pyogenes
  • Coagulase negative staph
  • Proteus mirabilis
  • Haemophilus influenza
  • Candida albicans
  • Neisseria gonorrhoeae
  • Bartonella henselae
  • Salmonella
  • Toxoplasma gondii

Most common cause of infective arthritis in teenagers and young adults

A

Neisseria gonorrhoeae

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13
Q

Choose the most appropriate answer from the list

  • Staphylococcus aureus
  • Borrelia burgdorferi
  • Escherichia coli
  • Brucella abortus
  • Pseudomonas aeruginosa
  • Mycobacterium tuberculosis
  • Kingella kingae
  • Streptococcus pyogenes
  • Coagulase negative staph
  • Proteus mirabilis
  • Haemophilus influenza
  • Candida albicans
  • Neisseria gonorrhoeae
  • Bartonella henselae
  • Salmonella
  • Toxoplasma gondii

Most commonly involves the vertebral column in adults and associated with wedging and/or collapse of vertebrae

A

Mycobacterium tuberculosis

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14
Q

Choose the most appropriate answer from the list

  • Staphylococcus aureus
  • Borrelia burgdorferi
  • Escherichia coli
  • Brucella abortus
  • Pseudomonas aeruginosa
  • Mycobacterium tuberculosis
  • Kingella kingae
  • Streptococcus pyogenes
  • Coagulase negative staph
  • Proteus mirabilis
  • Haemophilus influenza
  • Candida albicans
  • Neisseria gonorrhoeae
  • Bartonella henselae
  • Salmonella
  • Toxoplasma gondii

Most common cause of prosthetic joint infection

A

Coagulase negative staph

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15
Q

A 28 year old IV drug user presents to A&E with fever and back pain. He prepares his drugs using tap water and does not clean his skin prior to injecting. On examination, he was pyrexial at 40 degree Celsius, pan-systolic murmur on auscultation and tenderness over his thoracic spine on percussion.

Rank the following causative organisms given the above information, putting the MOST LIKELY organism first, and the least likely organism last.

A) Streptococcus pyogenes

B) Candida albicans

C) Escherichia coli

D) Staphylococcus aureus

E) Pseudomonas aeruginosa

A
Staphylococcus aureus
Streptococcus pyogenes
Pseudomonas aeruginosa
Escherichia coli
Candida albicans
Pseudomonas aeruginosa
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