Respiratory disease Flashcards

1
Q

Choose the most appropriate answer from the list

  • K-ras
  • Small cell carcinoma
  • Large cell carcinoma
  • EGFR
  • Squamous cell carcinoma
  • ERCC1
  • Adenocarcinoma
  • EML4-ALK1

TKIs such as Erlotinib, may be useful against this mutation.

A

EGFR

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2
Q

Choose the most appropriate answer from the list

  • K-ras
  • Small cell carcinoma
  • Large cell carcinoma
  • EGFR
  • Squamous cell carcinoma
  • ERCC1
  • Adenocarcinoma
  • EML4-ALK1

This mutation renders the tumour resistant to cisplatin.

A

ERCC1

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3
Q

Choose the most appropriate answer from the list

  • K-ras
  • Small cell carcinoma
  • Large cell carcinoma
  • EGFR
  • Squamous cell carcinoma
  • ERCC1
  • Adenocarcinoma
  • EML4-ALK1

No glandular or squamous differentiation on histological analysis, but squamous differentiation seen on electron microscopy.

A

Large cell carcinoma

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4
Q

Choose the most appropriate answer from the list

  • K-ras
  • Small cell carcinoma
  • Large cell carcinoma
  • EGFR
  • Squamous cell carcinoma
  • ERCC1
  • Adenocarcinoma
  • EML4-ALK1

Malignant cells can show signs of keratinisation.

A

Squamous cell carcinoma

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5
Q

Choose the most appropriate answer from the list

  • K-ras
  • Small cell carcinoma
  • Large cell carcinoma
  • EGFR
  • Squamous cell carcinoma
  • ERCC1
  • Adenocarcinoma
  • EML4-ALK1

Some patients with this type of tumour can develop fatal haemorrhage if taking bevacizumab.

A

Squamous cell carcinoma

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