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Path questions imperialendo.co.uk > Immune response to infection > Flashcards

Immune response to infection Flashcards

1
Q

Choose the most appropriate answer from the list.

  • b (1,3) glucan
  • Lactoferrin
  • Dermatan sulphate
  • Liposaccharide
  • Fibromodulin
  • Mycobactin
  • Granzyme
  • Mycolic acid
  • Heparan sulphate proteoglycan
  • Opsonin
  • Hepcidin
  • Perforin
  • Hyaluronan
  • Teichoic acid
  • Hydrochlorous acid
  • Uric acid

A compound found in its highest concentration in colostrum, which exerts antiviral effects by binding to cell surface lipoproteins. It also exerts antibacterial effect via sequestering free iron and prevents the development of biofilms in cystic fibrosis.

A

Lactoferrin

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2
Q

Choose the most appropriate answer from the list.

  • b (1,3) glucan
  • Lactoferrin
  • Dermatan sulphate
  • Liposaccharide
  • Fibromodulin
  • Mycobactin
  • Granzyme
  • Mycolic acid
  • Heparan sulphate proteoglycan
  • Opsonin
  • Hepcidin
  • Perforin
  • Hyaluronan
  • Teichoic acid
  • Hydrochlorous acid
  • Uric acid

An efficacious biological oxidant defending against microbial invasion.

A

Hydrochlorous acid

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3
Q

Choose the most appropriate answer from the list.

  • b (1,3) glucan
  • Lactoferrin
  • Dermatan sulphate
  • Liposaccharide
  • Fibromodulin
  • Mycobactin
  • Granzyme
  • Mycolic acid
  • Heparan sulphate proteoglycan
  • Opsonin
  • Hepcidin
  • Perforin
  • Hyaluronan
  • Teichoic acid
  • Hydrochlorous acid
  • Uric acid

A substance found on the cell wall of gram-positive bacteria which binds to C3, eventually leading to the formation of the membrane attack complex.

A

Teichoic acid

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4
Q

Choose the most appropriate answer from the list.

  • b (1,3) glucan
  • Lactoferrin
  • Dermatan sulphate
  • Liposaccharide
  • Fibromodulin
  • Mycobactin
  • Granzyme
  • Mycolic acid
  • Heparan sulphate proteoglycan
  • Opsonin
  • Hepcidin
  • Perforin
  • Hyaluronan
  • Teichoic acid
  • Hydrochlorous acid
  • Uric acid

Found in the granules of CD8+ T cells, this compound exerts direct cytotoxic effects by insertion into the plasma membrane of the target cell and formation of a pore.

A

Perforin

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5
Q

Choose the most appropriate answer from the list.

  • b (1,3) glucan
  • Lactoferrin
  • Dermatan sulphate
  • Liposaccharide
  • Fibromodulin
  • Mycobactin
  • Granzyme
  • Mycolic acid
  • Heparan sulphate proteoglycan
  • Opsonin
  • Hepcidin
  • Perforin
  • Hyaluronan
  • Teichoic acid
  • Hydrochlorous acid
  • Uric acid

Recognised by Natural Killer cells, this group of compounds is found in the cell membrane and extracellular matrix. Members of this family include syndecan and betaglycan.

A

Heparan sulphate proteoglycan

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6
Q

Choose the most appropriate answer from the list.

  • CCL19
  • Il-10
  • CCR7
  • Il-12
  • CD25
  • Il-2
  • CD4
  • Il-23
  • CD40L
  • Il-4
  • CD8
  • Il-6
  • FoxP3
  • Il-8
  • IFNg
  • TGF-beta

In combination with Il-6, this cytokine polarizes towards a cellular response that leads to Il-17 production

A

TGF-beta

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7
Q

Choose the most appropriate answer from the list.

  • CCL19
  • Il-10
  • CCR7
  • Il-12
  • CD25
  • Il-2
  • CD4
  • Il-23
  • CD40L
  • Il-4
  • CD8
  • Il-6
  • FoxP3
  • Il-8
  • IFNg
  • TGF-beta

This cytokine is key in driving the T cell response to extracellular pathogens

A

Il-4

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8
Q

Choose the most appropriate answer from the list.

  • CCL19
  • Il-10
  • CCR7
  • Il-12
  • CD25
  • Il-2
  • CD4
  • Il-23
  • CD40L
  • Il-4
  • CD8
  • Il-6
  • FoxP3
  • Il-8
  • IFNg
  • TGF-beta

This chemokine directs dendritic cell trafficking to lymph nodes

A

CCL19

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9
Q

Choose the most appropriate answer from the list.

  • CCL19
  • Il-10
  • CCR7
  • Il-12
  • CD25
  • Il-2
  • CD4
  • Il-23
  • CD40L
  • Il-4
  • CD8
  • Il-6
  • FoxP3
  • Il-8
  • IFNg
  • TGF-beta

This cytokine when expressed in combination with FoxP3 and CD4 is typical of Treg cells

A

CD25

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10
Q

Choose the most appropriate answer from the list.

  • CCL19
  • Il-10
  • CCR7
  • Il-12
  • CD25
  • Il-2
  • CD4
  • Il-23
  • CD40L
  • Il-4
  • CD8
  • Il-6
  • FoxP3
  • Il-8
  • IFNg
  • TGF-beta

This cell surface antigen plays an important role in promoting the key responses to viral infections, during which the ligand with which it interacts is downregulated

A

CD8

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11
Q

Choose the most appropriate answer from the list.

  • CD8 T cells
  • IgG
  • C1
  • IgM
  • C3
  • Macrophages
  • C5a
  • Natural Killer Cells
  • C9
  • Neutrophils
  • Dendritic Cells
  • Pre-B Cells
  • IgA
  • T-Helper 1 Cells
  • IgE
  • T-Regulatory Cells

Polymorphonuclear cells capable of phagocytosing pathogens (killing via oxidative and non-oxidative mechanisms)

A

Neutrophils

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12
Q

Choose the most appropriate answer from the list.

  • CD8 T cells
  • IgG
  • C1
  • IgM
  • C3
  • Macrophages
  • C5a
  • Natural Killer Cells
  • C9
  • Neutrophils
  • Dendritic Cells
  • Pre-B Cells
  • IgA
  • T-Helper 1 Cells
  • IgE
  • T-Regulatory Cells

A type of cell derived from monocytes and are resident in the peripheral tissues.

A

Macrophages

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13
Q

Choose the most appropriate answer from the list.

  • CD8 T cells
  • IgG
  • C1
  • IgM
  • C3
  • Macrophages
  • C5a
  • Natural Killer Cells
  • C9
  • Neutrophils
  • Dendritic Cells
  • Pre-B Cells
  • IgA
  • T-Helper 1 Cells
  • IgE
  • T-Regulatory Cells

Present in mucous to help provide a constitutive barrier to infection. A type of divalent antibody.

A

IgA

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14
Q

Choose the most appropriate answer from the list.

  • CD8 T cells
  • IgG
  • C1
  • IgM
  • C3
  • Macrophages
  • C5a
  • Natural Killer Cells
  • C9
  • Neutrophils
  • Dendritic Cells
  • Pre-B Cells
  • IgA
  • T-Helper 1 Cells
  • IgE
  • T-Regulatory Cells

Binding of immune complexes to this protein triggers the classical pathway of complement activation.

A

C1

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Path questions imperialendo.co.uk (44 decks)

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