Blood transfusion

Question 1

Choose the most appropriate answer from the list.

• Allogeneic blood transfusion O negative
• Fresh frozen plasma
• Allogeneic blood transfusion cross-matched
• Irradiated blood cells
• Antigen negative blood
• Platelets
• Autologous blood transfusion
• Washed red blood cells
• CMV Negative Blood
• Cryoprecipitate
• Fractionated fIX
• Fractionated fVIII

A 32 year old man comes into hospital by ambulance after being involved in a road traffic accident. He is unconscious and two obvious fractures of his femur and tibia and fibula. In his wallet, a nurse finds a blood donor card stating his blood type is AB positive. What will you use to replace the lost blood volume initially?

Answer 1

Allogeneic blood transfusion O negative

Question 2

Choose the most appropriate answer from the list.

• Allogeneic blood transfusion O negative
• Fresh frozen plasma
• Allogeneic blood transfusion cross-matched
• Irradiated blood cells
• Antigen negative blood
• Platelets
• Autologous blood transfusion
• Washed red blood cells
• CMV Negative Blood
• Cryoprecipitate
• Fractionated fIX
• Fractionated fVIII

A five year old boy comes into A+E with multiple bruises and haemarthrosis of both knees. After comforting the child and running tests, you find out he has haemophilia A. What treatment will you use in the long-term?

Answer 2

Fractionated fVIII

Question 3

Choose the most appropriate answer from the list.

• Allogeneic blood transfusion O negative
• Fresh frozen plasma
• Allogeneic blood transfusion cross-matched
• Irradiated blood cells
• Antigen negative blood
• Platelets
• Autologous blood transfusion
• Washed red blood cells
• CMV Negative Blood
• Cryoprecipitate
• Fractionated fIX
• Fractionated fVIII

A neonate is kept in the ICU as he appeared jaundice from birth and had signs of distress. Although he is slightly better now, his haemoglobin is still very low. What will you do to help him?

Answer 3

CMV Negative Blood

Question 4

Choose the most appropriate answer from the list.

• Allogeneic blood transfusion O negative
• Fresh frozen plasma
• Allogeneic blood transfusion cross-matched
• Irradiated blood cells
• Antigen negative blood
• Platelets
• Autologous blood transfusion
• Washed red blood cells
• CMV Negative Blood
• Cryoprecipitate
• Fractionated fIX
• Fractionated fVIII

Post-operatively, a 45 year old woman has developed bleeding from the wound site causing her haemoglobin and blood volume to drop significantly. Her coagulation tests show an abnormal PT and APTT. What is best used to help her bleeding?

Answer 4

Fresh frozen plasma

Question 5

Choose the most appropriate answer from the list.

• Allogeneic blood transfusion O negative
• Fresh frozen plasma
• Allogeneic blood transfusion cross-matched
• Irradiated blood cells
• Antigen negative blood
• Platelets
• Autologous blood transfusion
• Washed red blood cells
• CMV Negative Blood
• Cryoprecipitate
• Fractionated fIX
• Fractionated fVIII

A 27 year old lady requires a blood transfusion as her haemoglobin has dropped low. Before starting transfusion, she tells you she is IgA deficient. What treatment does she require?

Answer 5

Washed red blood cells

Question 6

Choose the most appropriate answer from the list.

• Bacterial complication of transfusion
• Immediate haemolytic transfusion reaction
• Delayed haemolytic transfusion reaction (DHTR)
• Transfusion Associated Circulatory Overload (TACO)
• Allergic reaction
• Post-transfusion purpura
• Febrile non-haemolytic transfusion reaction
• Transfusion related acute lung injury (TRALI)
• Transfusion associated dyspnoea (TAD)
• Iron overload
• Transfusion associated graft versus host disease
• Infectious complication

A 65-year-old woman with a history of hospital admissions due to cardiac disease has a blood transfusion. Shortly afterwards, you note she is short of breath. Her blood pressure is 150/95 and she has swollen feet.

Answer 6

Transfusion Associated Circulatory Overload (TACO)

Question 7

Choose the most appropriate answer from the list.

• Bacterial complication of transfusion
• Immediate haemolytic transfusion reaction
• Delayed haemolytic transfusion reaction (DHTR)
• Transfusion Associated Circulatory Overload (TACO)
• Allergic reaction
• Post-transfusion purpura
• Febrile non-haemolytic transfusion reaction
• Transfusion related acute lung injury (TRALI)
• Transfusion associated dyspnoea (TAD)
• Iron overload
• Transfusion associated graft versus host disease
• Infectious complication

A 25-year-old man with thalassaemia major complains of joint pain, polyuria and is jaundiced.

Answer 7

Iron overload

Question 8

Choose the most appropriate answer from the list.

• Bacterial complication of transfusion
• Immediate haemolytic transfusion reaction
• Delayed haemolytic transfusion reaction (DHTR)
• Transfusion Associated Circulatory Overload (TACO)
• Allergic reaction
• Post-transfusion purpura
• Febrile non-haemolytic transfusion reaction
• Transfusion related acute lung injury (TRALI)
• Transfusion associated dyspnoea (TAD)
• Iron overload
• Transfusion associated graft versus host disease
• Infectious complication

Mr. JG had a blood transfusion 2 hours ago. He is now pyrexial and hypotensive. There is another man in the bay having a blood transfusion today – his name is Mr. GJ.

Answer 8

Immediate haemolytic transfusion reaction

Question 9

Choose the most appropriate answer from the list.

• Bacterial complication of transfusion
• Immediate haemolytic transfusion reaction
• Delayed haemolytic transfusion reaction (DHTR)
• Transfusion Associated Circulatory Overload (TACO)
• Allergic reaction
• Post-transfusion purpura
• Febrile non-haemolytic transfusion reaction
• Transfusion related acute lung injury (TRALI)
• Transfusion associated dyspnoea (TAD)
• Iron overload
• Transfusion associated graft versus host disease
• Infectious complication

Mrs. X had a blood transfusion 2 weeks ago following unexpected blood loss during surgery. She has returned to A&E today with a fever and jaundice and she claims her urine is a weird colour. A FBC shows she is anaemic.

Answer 9

Delayed haemolytic transfusion reaction (DHTR)

Question 10

Choose the most appropriate answer from the list.

• Bacterial complication of transfusion
• Immediate haemolytic transfusion reaction
• Delayed haemolytic transfusion reaction (DHTR)
• Transfusion Associated Circulatory Overload (TACO)
• Allergic reaction
• Post-transfusion purpura
• Febrile non-haemolytic transfusion reaction
• Transfusion related acute lung injury (TRALI)
• Transfusion associated dyspnoea (TAD)
• Iron overload
• Transfusion associated graft versus host disease
• Infectious complication

A 35-year-old mother of four had a blood transfusion a week ago. She has subsequently developed antibodies to the HPA-1a antigen.

Answer 10

Post-transfusion purpura