Bone Flashcards

1
Q

Choose the most appropriate answer from the list

  • Ewing’s Sarcoma
  • Osteomyelitis
  • Fibrous Dysplasia
  • Osteopaenia
  • Hyperparathyroidism
  • Osteoporosis
  • Multiple Myeloma
  • Paget’s Disease
  • Non accidental injury
  • Renal Osteodystrophy
  • Osteoarthritis
  • Rickets
  • Osteogenesis Imperfecta
  • Osteomalacia

A 14 year old boy presents with pain and swelling in the right thigh. Bone biopsy shows small round blue tumour cells.

A

Ewing’s Sarcoma

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2
Q

Choose the most appropriate answer from the list

  • Ewing’s Sarcoma
  • Osteomyelitis
  • Fibrous Dysplasia
  • Osteopaenia
  • Hyperparathyroidism
  • Osteoporosis
  • Multiple Myeloma
  • Paget’s Disease
  • Non accidental injury
  • Renal Osteodystrophy
  • Osteoarthritis
  • Rickets
  • Osteogenesis Imperfecta
  • Osteomalacia

A 3 year old girl presents with a broken arm. Her father says he doesn’t know what happened, but he thinks she fell in the playground. She has been admitted with fractures before. On examination, her sclera appear bluish in colour.

A

Osteogenesis Imperfecta

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3
Q

Choose the most appropriate answer from the list

  • Ewing’s Sarcoma
  • Osteomyelitis
  • Fibrous Dysplasia
  • Osteopaenia
  • Hyperparathyroidism
  • Osteoporosis
  • Multiple Myeloma
  • Paget’s Disease
  • Non accidental injury
  • Renal Osteodystrophy
  • Osteoarthritis
  • Rickets
  • Osteogenesis Imperfecta
  • Osteomalacia

A 65 year old man of African American origin presents with back pain. He has also recently begun experiencing symptoms of renal failure. Blood tests show a normocytic, normochromic anaemia, and a raised ESR. Urinary analysis shows the presence of Bence Jones protein.

A

Multiple Myeloma

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4
Q

Choose the most appropriate answer from the list

  • Ewing’s Sarcoma
  • Osteomyelitis
  • Fibrous Dysplasia
  • Osteopaenia
  • Hyperparathyroidism
  • Osteoporosis
  • Multiple Myeloma
  • Paget’s Disease
  • Non accidental injury
  • Renal Osteodystrophy
  • Osteoarthritis
  • Rickets
  • Osteogenesis Imperfecta
  • Osteomalacia

A 72 year old woman presents with bone pain and a wrist fracture. On examination you notice an active AV fistula on the other wrist. Blood tests show low calcium, high phosphate and high PTH.

A

Renal Osteodystrophy

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5
Q

Choose the most appropriate answer from the list

  • Ewing’s Sarcoma
  • Osteomyelitis
  • Fibrous Dysplasia
  • Osteopaenia
  • Hyperparathyroidism
  • Osteoporosis
  • Multiple Myeloma
  • Paget’s Disease
  • Non accidental injury
  • Renal Osteodystrophy
  • Osteoarthritis
  • Rickets
  • Osteogenesis Imperfecta
  • Osteomalacia

A 40 year old woman presents with bone pain. Her past medical history includes right arm fracture, renal stones, and recurrent depression. Blood tests reveal high calcium, low phosphate and high PTH.

A

Hyperparathyroidism

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6
Q

Choose the most appropriate answer from the list

  • Avascular Necrosis
  • Increased Bone Formation
  • Normal Bone Mass
  • Decreased Bone Turnover
  • Stress Fracture
  • Increased Calcium In Bone
  • Osteophyte Formation
  • Slipped Epiphysis
  • Increased Angiogenesis
  • Colles’ Fracture
  • Increased Bone Turnover
  • Disrupted Trabecula Bone
  • Sub-Chondral Sclerosis
  • Vertebral Collapse
  • Decreased Calcium In Bone
  • Reduced Bone Mass

Which of the above may be a feature in a patient with osteomalacia but not in an osteoporotic patient?

A

Decreased Calcium In Bone

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7
Q

Choose the most appropriate answer from the list

  • Avascular Necrosis
  • Increased Bone Formation
  • Normal Bone Mass
  • Decreased Bone Turnover
  • Stress Fracture
  • Increased Calcium In Bone
  • Osteophyte Formation
  • Slipped Epiphysis
  • Increased Angiogenesis
  • Colles’ Fracture
  • Increased Bone Turnover
  • Disrupted Trabecula Bone
  • Sub-Chondral Sclerosis
  • Vertebral Collapse
  • Decreased Calcium In Bone
  • Reduced Bone Mass

Which of the abnormalities above would be found on investigation of a patient with osteitis fibrosa cystica?

A

Increased Calcium In Bone

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8
Q

Choose the most appropriate answer from the list

  • Avascular Necrosis
  • Increased Bone Formation
  • Normal Bone Mass
  • Decreased Bone Turnover
  • Stress Fracture
  • Increased Calcium In Bone
  • Osteophyte Formation
  • Slipped Epiphysis
  • Increased Angiogenesis
  • Colles’ Fracture
  • Increased Bone Turnover
  • Disrupted Trabecula Bone
  • Sub-Chondral Sclerosis
  • Vertebral Collapse
  • Decreased Calcium In Bone
  • Reduced Bone Mass

An elderly male patient sees you at your GP clinic complaining of sciatic pain and headaches. He said his motorcycle helmet no longer fits him. Which of the above are you likely to find on investigation?

A

Increased Bone Formation

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9
Q

Choose the most appropriate answer from the list

  • Avascular Necrosis
  • Increased Bone Formation
  • Normal Bone Mass
  • Decreased Bone Turnover
  • Stress Fracture
  • Increased Calcium In Bone
  • Osteophyte Formation
  • Slipped Epiphysis
  • Increased Angiogenesis
  • Colles’ Fracture
  • Increased Bone Turnover
  • Disrupted Trabecula Bone
  • Sub-Chondral Sclerosis
  • Vertebral Collapse
  • Decreased Calcium In Bone
  • Reduced Bone Mass

An elderly lady is brought to A&E following a fall on to an outstretched hand. She has been on steroid treatment for rheumatoid arthritis for many years. She now complains of pins and needles in her legs. What should you investigate for?

A

Vertebral Collapse

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10
Q

Choose the most appropriate answer from the list

  • Avascular Necrosis
  • Increased Bone Formation
  • Normal Bone Mass
  • Decreased Bone Turnover
  • Stress Fracture
  • Increased Calcium In Bone
  • Osteophyte Formation
  • Slipped Epiphysis
  • Increased Angiogenesis
  • Colles’ Fracture
  • Increased Bone Turnover
  • Disrupted Trabecula Bone
  • Sub-Chondral Sclerosis
  • Vertebral Collapse
  • Decreased Calcium In Bone
  • Reduced Bone Mass

A confused patient tells you that she doesn’t want to take her medicine because she doesn’t know what it’s for. She shows you that she is taking Strontium, what abnormality above is the most likely to be present?

A

Reduced Bone Mass

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11
Q

Choose the most appropriate answer from the list

  • Osteopenia
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Osteomalacia
  • Paget’s Disease
  • Geode
  • Osteogenesis imperfecta
  • Osteopetrosis
  • Multiple myeloma
  • Chondrosarcoma
  • Osteitis Fibrosis Cystica
  • Osteoporosis
  • Hyperparathyroidism
  • Gout

A horizontal fracture in Looser’s Zone is pathognomonic

A

Osteomalacia

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12
Q

Choose the most appropriate answer from the list

  • Osteopenia
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Osteomalacia
  • Paget’s Disease
  • Geode
  • Osteogenesis imperfecta
  • Osteopetrosis
  • Multiple myeloma
  • Chondrosarcoma
  • Osteitis Fibrosis Cystica
  • Osteoporosis
  • Hyperparathyroidism
  • Gout

A radiograph of the hand shows small resorptive lesions in the bones of the 4th and 5th digits

A

Hyperparathyroidism

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13
Q

Choose the most appropriate answer from the list

  • Osteopenia
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Osteomalacia
  • Paget’s Disease
  • Geode
  • Osteogenesis imperfecta
  • Osteopetrosis
  • Multiple myeloma
  • Chondrosarcoma
  • Osteitis Fibrosis Cystica
  • Osteoporosis
  • Hyperparathyroidism
  • Gout

A mixed picture of lytic lesions and microfractures are seen on X-ray in a 54yr old Caucasian man presenting with cardiac failure

A

Paget’s Disease

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14
Q

Choose the most appropriate answer from the list

  • Osteopenia
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Osteomalacia
  • Paget’s Disease
  • Geode
  • Osteogenesis imperfecta
  • Osteopetrosis
  • Multiple myeloma
  • Chondrosarcoma
  • Osteitis Fibrosis Cystica
  • Osteoporosis
  • Hyperparathyroidism
  • Gout

Hyperparathyroidism can lead to which other condition listed above (also known as Von Recklinghausen’s Disease of Bone)?

A

Osteitis Fibrosis Cystica

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15
Q

Choose the most appropriate answer from the list

  • Osteopenia
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Osteomalacia
  • Paget’s Disease
  • Geode
  • Osteogenesis imperfecta
  • Osteopetrosis
  • Multiple myeloma
  • Chondrosarcoma
  • Osteitis Fibrosis Cystica
  • Osteoporosis
  • Hyperparathyroidism
  • Gout

Can result in widened epiphyseal plates

A

Osteomalacia

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16
Q

Choose the most appropriate answer from the list

  • Nullparity
  • Osteocytes
  • Moderate alcohol intake
  • Increased PO4 excretion and Ca absorption
  • Osteoclasts
  • Increased PO4 and Ca absorption
  • T score between -1 and -2.5 SD
  • Increased PO4 and Ca excretion
  • Osteoblasts
  • T score >-2.5 SD
  • Z score >-2.5 SD
  • Z score between -1 and -2.5 SD
  • Malabsorption

Classifies “osteopaenia”

A

T score between -1 and -2.5 SD

17
Q

Choose the most appropriate answer from the list

  • Nullparity
  • Osteocytes
  • Moderate alcohol intake
  • Increased PO4 excretion and Ca absorption
  • Osteoclasts
  • Increased PO4 and Ca absorption
  • T score between -1 and -2.5 SD
  • Increased PO4 and Ca excretion
  • Osteoblasts
  • T score >-2.5 SD
  • Z score >-2.5 SD
  • Z score between -1 and -2.5 SD
  • Malabsorption

Excess PTH’s effect on the kidneys

A

Increased PO4 excretion and Ca absorption

18
Q

Choose the most appropriate answer from the list

  • Nullparity
  • Osteocytes
  • Moderate alcohol intake
  • Increased PO4 excretion and Ca absorption
  • Osteoclasts
  • Increased PO4 and Ca absorption
  • T score between -1 and -2.5 SD
  • Increased PO4 and Ca excretion
  • Osteoblasts
  • T score >-2.5 SD
  • Z score >-2.5 SD
  • Z score between -1 and -2.5 SD
  • Malabsorption

A risk factor for osteoporosis

A

Malabsorption

19
Q

Choose the most appropriate answer from the list

  • Nullparity
  • Osteocytes
  • Moderate alcohol intake
  • Increased PO4 excretion and Ca absorption
  • Osteoclasts
  • Increased PO4 and Ca absorption
  • T score between -1 and -2.5 SD
  • Increased PO4 and Ca excretion
  • Osteoblasts
  • T score >-2.5 SD
  • Z score >-2.5 SD
  • Z score between -1 and -2.5 SD
  • Malabsorption

Classifies Osteoporosis

A

T score >-2.5 SD

20
Q

Choose the most appropriate answer from the list

  • Nullparity
  • Osteocytes
  • Moderate alcohol intake
  • Increased PO4 excretion and Ca absorption
  • Osteoclasts
  • Increased PO4 and Ca absorption
  • T score between -1 and -2.5 SD
  • Increased PO4 and Ca excretion
  • Osteoblasts
  • T score >-2.5 SD
  • Z score >-2.5 SD
  • Z score between -1 and -2.5 SD
  • Malabsorption

“Macrophages” of the bone

A

Osteoclasts

21
Q

Choose the most appropriate answer from the list

  • Comminuted fracture
  • Paget’s disease
  • Compound fracture
  • Pott’s disease
  • Gout
  • Pseudogout
  • Lyme disease
  • Rheumatoid arthritis
  • Osteoarthritis
  • Rickets
  • Osteomyelitis
  • Scleroderma
  • Osteopaenia
  • Sjogren’s disease
  • Osteoporosis
  • Systemic Lupus Erythematosus

Splintered bone with intact soft tissue

A

Comminuted fracture

22
Q

Choose the most appropriate answer from the list

  • Comminuted fracture
  • Paget’s disease
  • Compound fracture
  • Pott’s disease
  • Gout
  • Pseudogout
  • Lyme disease
  • Rheumatoid arthritis
  • Osteoarthritis
  • Rickets
  • Osteomyelitis
  • Scleroderma
  • Osteopaenia
  • Sjogren’s disease
  • Osteoporosis
  • Systemic Lupus Erythematosus

Features include raised ESR, pannus formation and hyperextended proximal interphalangeal joints

A

Rheumatoid arthritis

23
Q

Choose the most appropriate answer from the list

  • Comminuted fracture
  • Paget’s disease
  • Compound fracture
  • Pott’s disease
  • Gout
  • Pseudogout
  • Lyme disease
  • Rheumatoid arthritis
  • Osteoarthritis
  • Rickets
  • Osteomyelitis
  • Scleroderma
  • Osteopaenia
  • Sjogren’s disease
  • Osteoporosis
  • Systemic Lupus Erythematosus

Inflamed big toe with tophus and precipitate of needle shaped crystals

A

Gout

24
Q

Choose the most appropriate answer from the list

  • Comminuted fracture
  • Paget’s disease
  • Compound fracture
  • Pott’s disease
  • Gout
  • Pseudogout
  • Lyme disease
  • Rheumatoid arthritis
  • Osteoarthritis
  • Rickets
  • Osteomyelitis
  • Scleroderma
  • Osteopaenia
  • Sjogren’s disease
  • Osteoporosis
  • Systemic Lupus Erythematosus

Can present as malaise, fever, cough with vertebral collapse

A

Pott’s disease

25
Q

Choose the most appropriate answer from the list

  • Comminuted fracture
  • Paget’s disease
  • Compound fracture
  • Pott’s disease
  • Gout
  • Pseudogout
  • Lyme disease
  • Rheumatoid arthritis
  • Osteoarthritis
  • Rickets
  • Osteomyelitis
  • Scleroderma
  • Osteopaenia
  • Sjogren’s disease
  • Osteoporosis
  • Systemic Lupus Erythematosus

Associated with erythema chronicum migrans, cardiac arrhythmias and neurological symptoms

A

Lyme disease