wk 8 + 9 BB Flashcards
Nuerodiversity led to a paradigm shift, allowing for
a greater input from the autistic community and collaborative research practices
The social model of disability aligns with neurodiversity as it
it takes social and environmental factors into count
The medical model of disability assumes impairment and tries to
fix the problem
Markers of a universal theory must be
specific (apply to all members of group)
Sensitive (explain all features of the condition)
a universal theory tries to
explain one component that explains differences between groups
Differences in _____ _______ recognition in autistic community
potentially driven by
facial emotion
a subgroup eho performed poorer on a facial emotion recognition task, an who also showed differences in neural processing and clinically defined features of autism
Higher rates of ______ found in autistic people
alexithymia
also associated with higher clinically defined features of autism and increased levels of experienced anxiety
- _____% of the English population diagnosed autistic
0.82
DSM criteria autism
Differences in social communication and interaction
- Specific patterns of behaviour, passionate interests, or focused activities
- Sensory hyper- or hypo-sensitivities
Concordance rates of autism
Twins: MZ rates: 60%, DZ
rates: 5%;
Co-occurring diagnoses
are common in people
with autism across the
lifespan, e.g.:
ADHD (28%)
* Anxiety (20%)
* Depression (11%)
Fact: Most up-to-date
estimate ratio of autistic
males to females is
3:1.
“Girls who meet criteria for
[autism] are at disproportionate
risk of not receiving a clinical
diagnosis.”
Why ?
- Genetic differences and susceptibility
- Underdiagnosis of autistic women and girls
- Differences in characteristics and traits
- Camouflaging
Camouflaging Autistic Traits Questionnaire – CAT-Q
Three subscales:
Masking: strategies used to hide autistic characteristics or portray a non-autistic persona
Compensation: strategies used to actively compensate for difficulties in social situations
Assimilation: Strategies that reflect trying to fit in with others in social situations (the motivation)
which gender camouflages more
females
Theory of Mind:
: the ability to attribute independent mental
states to oneself and others to explain their behaviour
- Evidence for differences in mentalising at the neural level
is
inconsistent
The Double Empathy Problem can lead to
a breakdown in
mutual understanding between autistic and non-autistic
people
levels of acetylcholine are high in the
hippocampus and neocortex
acetylcholine role in sleep
where is this produced to cause this effect
activating AcH neurones in the basal forebrain causes wakefulness
i AcH high or low in slow wave sleep
low
Norepinephrine/Noradrenaline
Activity of noradrenergic locus coeruleus- neurons increases ______
vigilance
Norepinephrine increases or decreases during wakefulness
increases
how is serotonin involved in arousal.
how do concentrations change during sleep/wake cycle
serotonergic neurons are most active during waking, steadily decline during sleep to almost zero acivity in REM sleep.
The second after REM sleep, become very active