Weight Loss Flashcards

1
Q

How much of reduced calorie deficit does there need to be in order to reduce weight

A

500 to 750kcal daily deficit

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2
Q

How much physical activity should an individual engage on a weekly basis

A

150 minutes per week with 2 to 3 days dedicated to strength training

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3
Q

When would prescription drugs be appropriate for someone who is trying to lose weight

A

If their BMI is greater than 30 or their BMI is greater than 27 WITH ONE WEIGHT RELATED CONDITION

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4
Q

T/F: Weight loss medications should only be used adjunctive to diet and exercise lifestyle changes

A

True

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5
Q

What are the “long term” weight loss drugs

A

Phentermine AND Topiramate (Qysmia), Naltrexone AND Bupropion (Contrave), Liraglutide (Saxenda or Victoza), Orlistat (Xenical or Alli-OTC)

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6
Q

What is in Qysmia

A

Phentermine AND Topiramate

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7
Q

What are the contraindications to Qysmia (Phentermine/Topiramate)

A

Pregnancy, Hyperthyroidism, glaucoma and MAO inhibitor use within the past 14 days

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8
Q

What are the most common side effects of Qysmia

A

Insomnia, tingling in extremities (paresthesia), tachycardia

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9
Q

Why is Qysmia use associated with REMS, how is it applied

A

Use is associated with teratogenic risks, pregnancy test needed fefore treatment and monthly thereafter along with effective contraception during treatment

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10
Q

What is an important note about Qysmia (Phentermine/Topiramate)

A

Medication should be tapered due to seizure risk associated with topiramate use

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11
Q

What is in Contrave

A

Naltrexone AND Bupropion

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12
Q

What is the BBW for Contrave (Naltrexone and Bupropion)

A

Not approved for treating MDD or psychiatric disorders, increased risk of suicidal thinking and behavior in children adolescents and adults younger than 24, not approved for use in pediatric patients

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13
Q

What are the contraindications for Contrave (Naltrexone and Bupropion)

A

Pregnancy, opiod use or opiod use withdrawal, uncontrolled hypertension, seizure disorder, use of other bupropion products, bulimia and/or anorexia, abrupt discontinuation of alcohol benzos barbituates and antiepileptic drugs

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14
Q

What are the side effects of Contrave

A

N/V, headache, dizziness, dry mouth, insomnia

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15
Q

What is the important thing to note about Contrave (Naltrexone AND Bupropion)

A

Discontinue opiods or buprenorphine 7 to 14 days prior to use, Naltrexone blocks opiods

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16
Q

What is BBW for Saxenda and Victoza

A

Risk of thyroid C-cell carcinomas in animal studies, risk to humans unknown

17
Q

What are the contraindications to Saxenda and Victoza

A

Pregnancy, personal or family history or medullary thyroid carcinoma (MTC) or patients with Multiple Endrocrine Neoplasia syndrome Type 2 (MEN 2)

18
Q

What should patients be warned to be aware of when taking Saxena and Victoza

A

Pancreatitis, jypoglycemia, acute gallbladder disease, and gastroparesis (slows gastric empyting)

19
Q

What are the side effects associated with Liraglutide (Saxenda and Victoza)

A

Nausea, vomiting, abdominal pain and distension, dizziness

20
Q

What are the contraindications to using Orlistat

A

Pregnancy, cholestasis and chronic malabsorption

21
Q

What are the side effects of Orlistat (Xenicall and Alli)

A

FLATULENCE WITH DISCHARGE, FATTY STOOL, fecal urgency

22
Q

What is to note about using Orlistat and vitamins

A

Take multivitamines with A, D, E, and K at bedtime or separated by greater than 2 hours

23
Q

When should orlistat be taken

A

With every meal containing fat OR 1 hour after eating

24
Q

What are the older stimulant drugs that are used for “short-term” use and jumpstart a diet, what is their control status for each

A

Phentermine (Adipex-P)- CIV, Diethylpropion- CIV, Phendimetrazine- CIII, Benzphetamine- CIII

25
Q

What are the contraindications for “short term” wieght loss drugs

A

Cardiovascular disease, hyperthyroidism, glaucoma, pregnancy, drug abuse

26
Q

What are the adverse effects of the “short term” weight loss drugs

A

Tachycardia, agitation, and increase blood pressure

27
Q

T/F: All weight loss drugs should be DISCONTINUED if they do not produce at 10% weight loss at 24 weeks

A

False: All weight loss drugs should be DISCONTINUED if they do not produce 5% weight loss at 12 weeks

28
Q

T/F: Orlistat (Xenical and Alli) should be taken with a strict dietary plan with a max of 30% of kcals from fat

A

True