Antifungals and AntiVirals

Question 1

T/F: Amphotericin has less toxicity when it is formulated in a lipid solution

Answer 1

True

Question 2

What are the common side effects amphotericin

Answer 2

hypomagnesia, hypokalemia, and rigors

Question 3

What antifungal is the most dangerous for people who have a cardiac condition

Answer 3

Itraconazole

Question 4

What antifungal has a BBW regarding liver dysfunction

Answer 4

Ketoconazole

Question 5

What is the only antifungal that requires a dose adjustment

Answer 5

Fluconazole

Question 6

What antifungal can cause a histamine release reaction, what are the side effects

Answer 6

Micafungin/ drop in blood pressure, pruritus, flushing

Question 7

Which antifungals need an acidic enviornment

Answer 7

Ketoconazole and itraconazole

Question 8

What is the preferred antifungal for aspergillus

Answer 8

Voriconazole

Question 9

What is the MOA of oselmativir

Answer 9

Inhibits neuromidase

Question 10

What are the only two candida species that fluconazole should not be used for

Answer 10

Candida KRUSEI and Candida GLABRATA