Infectious Disease I Pt. 2 Flashcards
How is Nitrofurantoin dosed
BID
What is the CrCl that is contraindicated for Nitrofurantoin use
Less than 60 ml/min
T/F: Daptomycin can effect INR assay
True
Brand names for Daptomycin
Cubicin
What are the counseling tips for the Cyclines
Can cause drug induced lupus, The medication should be separated when given with antacids, Increased risk of sunburn
What antibiotic has a boxed warning about potentially causing a C.diff infection
Clindamycin
What is a serous side effect of Bactrim, how can it be tested for
Hemolytic Anemia, A Positive Coombs test
How long should a patient wait before taking metronidazole if drinking alcohol
At least 3 days from the last dose
What are counseling points for Quniolones
Monitor blood sugar, Increased risk of sunburn, avoid cations by two hours, increased risk of tendon rupture
T/F: Bactrim should be avoided with a G6PD deficiency
True
T/Fâ Bactrim has a 1:1 conversion from IV to oral
True
What is the brand name for Linezolid
Zyvox
What is the drug of choice for Acinetobacter
Meropenem
What is the max amount of Vancomycin that should be administered
1 gram over 1 hour
T/F: Rifaximin (Xifaxin) is not absorbed well systemically so it usually used for diarrhea and Hepatic encephalopathy
True
T/F: Step species is usually in pairs or chains
True
T/F: Linezolid is metabolized by the liver
True
T/F: Biaxin is associated with hepatotoxicity
True
What antibiotics are associated with ototoxicity
Gentamicin and Vancomycin
T/F: Quinolones are associated with peripheral neuropathies
True
If Vancomycin is used how low should the MIC
Less than 2 mcg/mL
What are the antibiotics classes that are associated with decreasing seizure threshold
Quinolones and betalactams (Penicillins, cephalosporins, and Carbepenems)
T/F: Bactrim is only compatible with D5W
True
What are the antibiotic classes associated with QT prolongation
Macrolides and Quinolones
What antibiotic classes are associated with covering atypicals
Quinolones, Tetracyclines, and Macrolides
What antibiotics cover VRE
Linezolid and Daptomycin
Which quinolones have the best activity against S. pneumonaie
Levofloxacin and Moxifloxacin
