Dyslipidemia Redo Flashcards

1
Q

What statins are most likely to have a drug drug interaction, what cant they be used

A

Lovastatin and Simvastatin, Azole antifungals, strong CYP3A4 inhibitors

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2
Q

If a patient has diabetes at the age of 40 and 75 with an LDL between 70 and 189 what type of statin should they receive, when would it be increased

A

Mid Intensity Statin, Having other commorbidities hypertension, smoking, and other ASCVD risk

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3
Q

T/F: Fenofirbrates can be used in pregnancy

A

True

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4
Q

Patients should have their ASCVD score redone every how many years if low risk

A

4 to 6 years

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5
Q

What parts of Lipid panels are used to determine ASCVD

A

Total cholesterol, LDL, and HDL

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6
Q

What medications classes are used more for triglycerides

A

Fish oils, Fibrates, Niacins

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7
Q

What is the MOA of zetia (ezitimbe)

A

Reduces blood cholesterol by inhibiting the absorption of cholesterol by the small intestine

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8
Q

What statins should be taken at night (Sam Hates the Flu)

A

Simvastatin, Lovastatin, and Fluvastatin

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9
Q

T/F: Bile acids raise triglycerides

A

True

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10
Q

T/F: Niacin increases uric acid, hepatoxicity and blood sugar

A

True

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11
Q

What class increases triglycerides

A

Bile acid sequestrants

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12
Q

What class increases blood sugar

A

Niacin

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13
Q

What is the MOA of Fenofibrates

A

PPAR activation

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14
Q

If a patient has an ASCVD risk greater than 20%

A

High intensity Statin

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15
Q

What is the equation to calculate LDL

A

LDL= TC- HDL - (TG/5)

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16
Q

T/F: Diuretics’ are associated with a rise in LDL and trigylcerides

A

True