Dyslipidemia Redo Flashcards
What statins are most likely to have a drug drug interaction, what cant they be used
Lovastatin and Simvastatin, Azole antifungals, strong CYP3A4 inhibitors
If a patient has diabetes at the age of 40 and 75 with an LDL between 70 and 189 what type of statin should they receive, when would it be increased
Mid Intensity Statin, Having other commorbidities hypertension, smoking, and other ASCVD risk
T/F: Fenofirbrates can be used in pregnancy
True
Patients should have their ASCVD score redone every how many years if low risk
4 to 6 years
What parts of Lipid panels are used to determine ASCVD
Total cholesterol, LDL, and HDL
What medications classes are used more for triglycerides
Fish oils, Fibrates, Niacins
What is the MOA of zetia (ezitimbe)
Reduces blood cholesterol by inhibiting the absorption of cholesterol by the small intestine
What statins should be taken at night (Sam Hates the Flu)
Simvastatin, Lovastatin, and Fluvastatin
T/F: Bile acids raise triglycerides
True
T/F: Niacin increases uric acid, hepatoxicity and blood sugar
True
What class increases triglycerides
Bile acid sequestrants
What class increases blood sugar
Niacin
What is the MOA of Fenofibrates
PPAR activation
If a patient has an ASCVD risk greater than 20%
High intensity Statin
What is the equation to calculate LDL
LDL= TC- HDL - (TG/5)