Week 2 Chapter 37 Flashcards
Types of Infectious Diseases
Bacterial
Viral
Zoonotic and Vector Borne
Parasitic and helminthic
STIs
Infectious process
Organism Enters and multiplies
Causes damage to tissues and cells
Body response -1. Vascular -2. Cellular
1st line of defense and phagocytic cells
Granulocytes
Neutrophils including
Bands, segs, and PMNs
Eosinophils, basophils
Produce and maintain immune response, respond to viral infections
Lymphocytes
Produce antibodies and bind to neutralize antigen
B Cell
T Cell
Attack antigen directly
NK cells (innate immunity)
Destroy foreign material
Second line of defense and responds to larger and more severe infections
Monocytes
Infection stimulates the release of the endogenous pyrogens
Fever
(interleukins, tumor necrosis factor, and interferon)
Pyrogens act on the hypothalamus and trigger prostaglandin production, which increases the body set of temperature
True
Vasoconstriction is response
Cold
Vasodilation is heat response
Decrease heat loss and allow the body’s temperature ….
Rise to the new set point resulting in fever
General Guidelines of fever
Any temperature above 38.1 C
Infants younger than 3 months >38C < 36C SEE DOCTOR!!!
How many times do you asses temperature?
Every 4-6 hours
Use same site and device
Assess I and Os
Keep linens and clothing clean and dry
Acetaminophen recommended dose
10-15 mg/ kg
Every 4-6 hours
Ibuprofen 5-10 mg/ kg dose
Every 6-8 hours
No more than 4 doses in 24 hour period
Stages of Infectious Diseases
Incubation - Entrance
Prodrome- Nonspecific symptoms
Illness- S/S of disease
Convalescence - Acute symptoms begin to disappear
Methods of Preventing Infectious Disease
Hand Washing
Adequate Immunizations
Proper Handling of food
Judicious Antibiotic
Chain of Infection
Infectious Agent
Reservoir
Portal of Exit
Mode of Transmission
Portal of Entry
Susceptible Host
Limiting Spread of Infections
Standard - Tier 1
Transmission based- Tier 2
Airborne
Droplet
Contact
Pediatric physiology and Immune System
More susceptible of infection
Newborns display decreased inflammatory response to invading organisms, contributing increased risk for infection
Infant limited exposure and loses passive immunity=Higher risk of infection
Cellular immunity is generally functional at birth
True
Humoral occurs when body encounters and then develops immunity to new disease
Disease protection from immunization is incomplete
Common Treatments and Medications for Infectious Disorders
Tx
Hydration and Fever Reduction
Medications
Antibiotics
Antivirals
Antipyretics
Antipruritic
What information is obtained in health Hx?
Past medical Hx, birth hx, family hx, previous illness or surgery
Hx of current illness
S/S
Any changes in usual behaviors
Any known exposure
Assessments made during a physical exam include
Inspection and observation
Skin, mouth, throat, and hair lesions or wounds
Hydration status and vital signs
Palpation
Skin
rash
lymph nodes
Common Labs for Infections
CBC
ESR
CRP
Blood Culture Sensitivity
Stool Culture
Urine Culture
Wound Culture
Throat Culture
Nasal Swabs
LP
Chest X Ray
Sepsis
Systemic overresponse to infection from bacteria and viruses and can lead to septic shock
Septic Shock can lead to
Hypotension, low blood flow, and multisystem organ failure
Most common causative agents
- E Coli, Group Strep, Staph A, Nessieria Meningitiidis
Infants less than 1 month of age, immunocompromised children, children with chronic condition, and children with an indwelling catheter are at a higher risk
True
Therapeutic Management of Sepsis
Admitted for close monitoring
IV antibiotics started immediately (after cultures obtained)
Lab and Diagnostic Tests for Sepsis
CBC Count: WBC Usually elevated
C Reactive Protein: Elevated
Blood Culture: Positive in Septicemia
Urine Culture: May be positive
CSF Analysis: May reveal increased WBCs and protein and low glucose
Stool Culture: May be positive for bacteria or other infectious organisms
Culture of tubes, catheters, or shunts suspected to be infected
Chest Radiograph: May reveal signs of pneumonia
Bacterial Infections
Children are at high risk of developing bacterial infections, which can result in life threatening illness
Community Acquired MRSA
Scarlet Fever
Diphtheria
Pertussis
Tetanus
Pertussis
Tetanus
Botulism
Osteomyelitis
Septic Arthritis
Minor skin rashes to abscesses to serious, life- threatening infections
- Sepsis, necrotizing pneumonia, osteomyelitis
CAMRSA
Direct person to person contact, resp. droplets, blood or sharing personal items (hairbrushes, towels, sports equipment)
CAMRSA
Best Barriers for CAMRSA
Intact Skin and mucous membranes
Proper hand hygiene
Diagnosis of CAMRSA
Through culture
I & D, aspiration, culture
Tx with antibiotics
Group A streptococci
Throat Infection (strep)
Scarlet Fever
Streptococcal skin infection (rare)
Bacteria produces a toxin that causes a rash