week 1 Flashcards

1
Q

What is Pathophysiology?

A

The study of the physiological changes in the body as a result of disease or injury

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2
Q

Pathology

A

the lab study of cell and tissue changes associated with disease

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3
Q

Pathogenesis

A

the events involved in the development of a disease

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4
Q

Primordial Prevention

A

targets social and economic policies effecting health

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5
Q

primary prevention

A

target risk factors leading to injury

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6
Q

secondary prevention

A

prevents injury and disease once exposure to risk factors occurs but still early preclinical stage

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7
Q

tertiary prevention

A

rehabilitating persons with injury disease to reduce complication

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8
Q

Etiology: The study of the cause(s) of a
disease

A

genetic, congenital defect, microorganism, immune dysfunction, metabolic dysfunction

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9
Q

Idiopathic

A

the cause of the disease is unknown

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10
Q

Iatrogenic

A

a treatment/procedure/error caused the disease

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11
Q

Predisposing Factors

A

risk factors/behaviours that promote development of a
disease

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12
Q

Prophylaxis

A

Measured taken to preserve health / prevent onset or progression of
disease

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13
Q

Characteristics of Disease

A
  • Onset can be sudden/acute/insidious
  • The disease itself can be acute or chronic
  • Diseases can be classified by various stages, states, and periods
  • Subclinical state, latent stage, incubation period, prodromal period
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14
Q

signs

A

something that can be measured

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15
Q

symptoms

A

a feeling

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16
Q

Disease Prognosis:

A

The probability for recovery vs other outcomes (based on the
average outcomes)

17
Q

Non-Communicable Disease

A

Not spread from person to person

18
Q

Communicable Disease

A

Infections that can be spread from person to person

19
Q

Epidemic

A

Higher than normal or expected number of cases of an infection disease within a given area

20
Q

Pandemic

A

Higher numbers around the world

21
Q

Endemic

A

Disease that is regularly found among particular population or in a certain area

22
Q

atrophy

A

cells shrink

23
Q

Metaplasia

A

one mature cell type replaced by a
different mature cell type

24
Q

Dysplasia

A

cells vary in size, shape, nuclear size, mitotic rate

25
Q

Neoplasia

A

uncontrolled/abnormal growth
* Benign vs. malignant

26
Q

Cell Injury

A
  • Ischemia, hypoxia
  • Physical agents, temperature, radiation
  • Mechanical damage (tear, pressure)
  • Chemical toxins
  • Microorganisms (bacteria, virus, parasites)
  • Nutritional deficits or excess
  • Imbalance of fluids or electrolytes
  • Build up of metabolites
27
Q

Mechanisms of Cell Injury (3 ways)

A

1) Free Radical Formation
2) Hypoxia/Ischemia and ATP depletion
3) Disruption of Ca homeostasis

28
Q

APOPTOSIS

A
  • Programmed
  • Self-Destruction by enzymatic digestion
  • Debris engulfed by phagocytes
29
Q

NECROSIS

A

Injury or disease lead to cell death