W3-5 Inhibitors of Cell Wall Synthesis Flashcards

1
Q

Daptomycin

A

depolarizes cell membrane (non-β-lactam)

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2
Q

Polymyxin B

A

poly-aggregates create membrane holes, spill contents spill out of cell (non-β-lactam)

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3
Q

Bacitracin

A

prevents dephosphorylation events that are used to build cell wall (non-β-lactam)

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4
Q

Vancomycin

A

transglycocelation (non-β-lactam)

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5
Q

Carbapenems

A
imipenem, meropenem
transpeptidase inhibitor (β-lactam)
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6
Q

Benzathine

A

IM penicillin injection

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7
Q

Probenecid

A

penicillin additive, slows excretion of weak acids

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8
Q

Naficillin and Dicloxicillin

Antistaphylococcal penicillins

A

penicillinase-resistant

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9
Q

Binds irreversibly to penicillinase

A

Clavulanate

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10
Q

Beta-lactamase inhibitors

A

Sulbactam and Tazobactam

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11
Q

Aminopenicillinases

A

Ampicillin and Amoxicillin

can pass through porin channels, also Gram (-)

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12
Q

Antipseudomonals

A

Ticarcillin and Piperacillin

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13
Q

Antiallergenic penicillin

A
Aztreonam
only Gram (-)
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14
Q

Cephalosporins

A

cef

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