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Foundations > W3-2 Intro Antibiotics > Flashcards

W3-2 Intro Antibiotics Flashcards

1
Q

Contrast bactericidal and bacteriostatic

A

bactericidal: kills bacteria
bacteriostatic: stops bacteria from replicating

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2
Q

Bacterial ribosomes are very similar to ribosomes found where in humans?

A

mitochondria

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3
Q

Therapeutic index

A

TD50 (toxic amt)
Therapeutic index= —————————————
ED50 (therapeutic amt)

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4
Q

Do you want a high or low therapeutic index?

A

high, the closer to 1 the TI is, the more dangerous it is

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5
Q

Three spectra for antibiotics

A

Narrow
Extended
Broad

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6
Q

Prophylaxis

A

prevent infection

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7
Q

Pre-emptive therapy

A

labs positive, pt nonsymptomatic

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8
Q

Empiric therapy

A

symptomatic infection but no organism identified

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9
Q

Definitive therapy

A

known organism

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10
Q

Suppressive therapy

A

continued after disease is controlled

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11
Q

Pharyngitis: most common cause

A

VIRUS

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12
Q

What does the rapid antigen detection test for strep look for?

A

C-carbohydrate

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13
Q

Catalase test

A

motitors degradation of H2O2, differentiates Staphylococci and Streptococci

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14
Q

Three results of hemolysis

A

beta: clearing around colonies
alpha: green ring
gama: no hemolysis

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15
Q

What is an efflux pump?

A

Annoying machinery that pumps expensive drugs out of bacteria

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16
Q

Intrinsic resistance

A

Absence or inaccessibility of target of drug action

17
Q

Acquired drug resistance

A

From genetic variability, selected for in presence of antibiotics

18
Q

Transformation

A

Changing circular DNA strand

19
Q

Transduction

A

From bacteriophage

20
Q

Conjugation

A

Sharing plasmids

21
Q

Transposition

A

Moving genes within genome

22
Q

Antibiotic susceptibility testing

A

Can be used diagnostically

23
Q

Minimum inhibitory concentration

A

lowest concentration that prevents visible growths

Foundations (32 decks)

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