W3-4 Viral, Fungal, and Parasite Pathogenesis

Question 1

Group IV virus type

Answer 1

+ssRNA

Question 2

Hepatitis C

Group-Family

Answer 2

Group IV-Flaviviridae

Question 3

T/F HepC has a tegument portion

Answer 3

F

Question 4

Host response mechanism to Class IV viruses

Answer 4

Question 5

What if dsRNA is detected inside the cell?

Answer 5

RIG-I recognizes it from surface of mitochondria and initiates idential response as TLR3

Question 6

NS3/4 A

Answer 6

Protease-ctivates viral proteins

Deactivates TLR3 and RIG-I defense mechanisms

Question 7

Viral disease mechanisms

Answer 7

1. Cytopathic effect: disrupts physiology
2. Host immune response: causes illness
3. Tumorigenesis: uncontrolled proliferation

(HPV)

Question 8

Fungi disease mechanisms

Answer 8

1. Overgrowth
2. Host immune response

Question 9

Protozoa disease mechanisms

Answer 9

1. Displacement
2. Cytopathic: disrupts normal physiology
3. Host immune response

Question 10

Helminths disease mechanisms

Answer 10

1. Displacement
2. Competition: nutrients with host
3. Host immune response