W3-3 Clostridium difficile case study

Question 1

C. diff bacterium type

Answer 1

gram (+) rod

Question 2

C. diff: anaerobic, aerobic, or facultative anaerobe?

Answer 2

anaerobic

Question 3

Product of anaerobic metabolism in C. diff

Answer 3

butyric acid, acetone, and derivatives

Question 4

How does C. diff reproduce?

Answer 4

endospores

Question 5

Does purell kill endospores?

Answer 5

NO

Question 6

Gold standard for C. diff diagnosis

Answer 6

cytotoxin assay

Question 7

Severe complication of C. diff in colon

Answer 7

semimembronous colitis

Question 8

Complication of toxic megacolon

Answer 8

being a great rock band name

pressing on diaphragm, makes breathing difficult

Question 9

Toxin A

Answer 9

enterotoxin

Question 10

Toxin B

Answer 10

cytotoxin: disrupts cytoskeleton and damages cell:cell boundries

Question 11

First line antibiotic for C. diff

Answer 11

Metronidazole

Question 12

Second line antibiotic for C. diff

Answer 12

Vancomycin

Question 13

What possible world-ending complication does the over prescription of vanco lead to?

Answer 13

MRSA