W3-1: Microbial structure Flashcards

1
Q

Who invented the first simple microscope?

A

Antony van Leeuwenhoek and Robert Hooke

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2
Q

Pasteur disproved which theory of microorganism generation?

A

Spontaneous generation

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3
Q

Koch’s 4 postulates

A
  1. pathogen present in all disease cases–absent in healthy
  2. grow in pure culture
  3. grown cells must cause disease in healthy animals
  4. reisolate cells-show they are the same
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4
Q

What is a virulence factor?

A

Anything that promotes infection

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5
Q

What was Fredrick Griffith’s experiment?

A
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6
Q

5 categories of infectious agents

A
  1. Helmniths (worms)
  2. Protozoa
  3. Fungi
  4. Bacteria
  5. Viruses
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7
Q

Why are dyp molecules generally positively charged?

A

so they better bond with the negative interior of cells

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8
Q

Steps in preparing a smear

A
  1. Spread culture
  2. Dry
  3. Heat fix
  4. Stain
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9
Q

6 types of bacteria

A
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10
Q

Gram stain results

A

(+) purple (crystal violet stain)

(-) redish-pink (crystal violet)

non-gram stainable: colorless

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11
Q

Gram (+) cell wall

A
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12
Q

Gram (-) cell wall

A
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13
Q

peptidoglycan (+) vs (-)

A

larger in gram (+) organisms

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14
Q

Components of peptidoglycan layer

A

linked peptides

sugars

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15
Q

Bacterial reproduction method

A

binary fission

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16
Q

Division plate name in bacteria

A

FtsZ ring

17
Q

Action of pennicillin

A

DD-transpeptidase inhibitor