Voiding dysfunction Flashcards

1
Q

conditions associated with OAB

A

Lack of estrogen (menopause)

obesity

pelvic organ prolapse

pelvic floor dysfunction

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2
Q

overflow incontinence

A

underactive detrusor with chronic retention and bladder overdistention

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3
Q

anatomic urethral obstructions

functional urethral obstructions

A

anatomic - prostatic enlargement

urethral stricture

poor incontinence surgery

functional (hyperactive sphincter)

neurogenic - detrusor sphincter dyssynergia

non-neurogenic - dysfunctional voiding

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3
Q

urinary incontinence due to sphincter =

A

stress urinary incontinence

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4
Q

guarding reflex

A

micturirtion reflex can be abolished by external sphincter contraction

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5
Q

OAB = ___ and leads to ____

A

OAB = detrusror overactivity leading to urge incontinence

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5
Q

causes of urinary retention due to detrusor

A

Neurogenic

myogenic

psychogenic

Rx - anticholinergics, a-agonists, narcotics

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7
Q

innvervation type

detrusor contractipon

internal sphincter relazation

A

detrusor contraction - parasympathetic

internal relaxation - sympathetic

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8
Q

CNS role

A

volluntary control

inhibition of reflex detrusor contraction

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9
Q

coordinates voiding - detrusor contraction, internal, external sphincter relaxation

A

pontine mucturition center

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10
Q

urinary incontinence due to detrusor =

A

overactive bladder / urge urinary incontinence

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11
Q

incontinence due to weakness of sphincter and supporting structures of neck and bladder

A

Stress urinary incontinence

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12
Q

causes / risk factors for Stress urinary incontinence

A

vaginal / pelvic trauma (births, surgery, trauma, vaginal prolapse)

lack of estrogen (menopause)

neurologic

radiation therapy > scarring

obesity

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13
Q

presentation OAB

A

spasms

urinary frequency + urgency

nocturia

incontinence - don’t reach toliet in time

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15
Q

management of retention

A

cathetar drainage (indwelling or intermittent

treat UTI

discontinue meds (anticholinergics)

relieve obstruction (alpha blockers to reduce sphincter tone, prostate surgery)

neuromodulation (for non-obstructive retention)

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16
Q

treatment stress incontinence

A

Kegels

weight loss

Duloexitine - 5HT+NE reuptake inhibitor > increase output to external sphincter

17
Q

pathophys of post-op retention

A

anesthetics (antichlinergics) inhibit detrusor

increased sympathetic tone / bladder neck contraction

18
Q

OAB treatment

A

Behavior - fluid management, kegels

Rx - antichilinergics (oxybutynin, tolterodine)

b-3 andrenergic agonist (myrbetriq)

19
Q

sympathetic role

A

facilitates urine storage

inhibition of detrusor (directic via B3 adrenergic)

(indirect via inhibition of parasymptathetic

contraction of internal sphincter / bladder neck (a adrenergic receptors)

20
Q

parasymptathetic role

A

facilitates micturition

direct motor action of detrusor contraction (ach, muscarinic receptors)

indirect facilitation of detrusor contraction via stretch receptors

21
Q

cause of OAB

A

UTI / inflammation

Neurologic - spinal cord injury, stroke MS

Metabolic (diabetes)

Urethral obstruction