Viral Hepatitis Flashcards
IGM signifies
Acute or recent infection
IgG signifies
Past infection
Immunisation response
Presence of passively acquired antibody after receiving blood products
Viral hepatitis is
Inflammation of the liver
Hepatitis type A
Faecal- oral transmission
Hepatitis type B
parenteraltransmission
HEP A what type infection
Not chronic
HEP E infection
Not usually chronic but can in immunocompromised
Which hepatitis can cause c bromide infection
B,C,D
Liver function test
Aminotransferases
Imaging for viral hepatitis
Fibroscan and ultrasound
Symptoms of viral hepatitis
Non specific symptoms
Malaise,fever,headaches
Anorexia,nausea and vomiting
Right upper quadrant abdominal pain
Dark urine and clay coloured faeces
Jaundice
Management of viral hepatitis
Antiviral agents
Immunomdulation
Why is hep A stable
Unenveloped hepatovirus
Diagnosis of hepatitis A
Detect HAV IGM in blood samples
When is HEP A infectious
Jaundice: considered infectious from 2 weeks before to 7 days after jaundice onset
Passive immunisation is?
Human normal immunoglobulin
Active immunisation
HEP A vaccine
Hep E enveloped.
Unenveloped
Hep e caught how
Food borne zoonosis (undercooked meat)
Transmission through blood transfusion
Hep E incubation period
6 weeks
Diagnosis of hep E
Detect HEV IGM in blood
HEV RNA detection and quantification
HEP BCD DIAGNOSTIC TEST
Serology - antibody and antigen tests
Genome detection and quantification
Genotyping
Hep B
Incubation
Transmission
Carrier state
6 weeks to 6 months
Sexual intercourse or blood
300 million carriers world wide
Hep B vaccination techniques
Passive immunisation# immunoglobulin
Active - recombinant vaccine
Delta hepatitis can work only when
RNA virus enveloped by HBsAg
Delta hepatitis described as a
Coinfection
HEP
Post transfusion non A non B hepatitis
Transmission- blood, sex
Hep c diagnostic test
HCV RNA detection test
HCV genotype
Antiviral
Hep C vaccine.
No vaccine
Antiviral drugs
