Rheumatoid Arthritis Flashcards
Rheumatoid arthritis triggers by
Genetic + environment
Susceptibility genes
HLA-DR1
HLA DR4
Signs of rheumatoid arthritis
Symmetrical swollen
Painful
Stiff joints especially in the morning
Common joints
Metacarphalangeal (MCP)
proximal interphalangeal (PIP)
Metarsophalangeal (mtp)
Other side effects
Fatigue fever weight loss
Flare up symptoms
Swollen
Warm
Red
Painful
Later symptoms
Ulcer deviation
Boutonnière
Swan neck
+Larger joints affected
Other symptoms
Rheumatoid nodules (elbow)
MI increase
Pleural effusions
Anaemia
Diagnosis
Rheumatoid factor
anti ccp
X Ray
Bone density decrease
Bony effusions
Soft tissue swelling
Narrowing joint space
MRI can detect what better
Synovitis
Treatment
DMARDS after 3 months of persistent symptoms
Methotrexate
Sulfasalazine
Hydroxychloroquine