vasculitis Flashcards
what are the two types of large vessel vasculitis?
Giant cell arteritis and takayasu arteritis
what is the demographic for giant cell arteritis
50+ year old Caucasian women
what is the demographic for takayasu arteritis
under 50 year old Asian women
what is GCA associated with?
polymyalgia rheumatica
what bloods are raised in large vessel vasculitis?
ESR, PV, CRP
how do you treat large vessel vasculitis?
steroids
what small vessel vasculitis are ANCA +ve
GPA, eosinophilia with polyangiitis, microscopic polyangiitis
which ANCA positive vasculitis have granulomas?
GPA and eosinophilia with polyangiitis
what is microscopic polyangiitis associated with?
glomerulonephritis
what vasculitis are pANCA and which are cANCA
pANCA = eosinophilia with polyangiitis + microscopic polyangiitis cANCA = GPA
what is eosinophilia with polyangiitis associated with?
asthma, eosinophilia, rhinitis, mononeuritis multiplex
what is GPA associated with
ENT symptoms (nose issues) and respiratory symptoms (haemoptysis, cavitating lesions on CXR)
what antibodies are associated with GPA?
PR3
what antibodies are associated with eosinophilia with polyangiitis?
MPO
what antibodies are associated with microscopic polyangiitis?
MPO
