Question bank random mix (part 2) Flashcards

1
Q

What electrolyte imbalance do thiazide diuretics cause?

A

hypercalcaemia

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2
Q

what change can macrolides (eg clarithromycin) cause on ECG?

A

Prolonged QT

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3
Q

what are the rules for tetanus cover following a potentially tetanus prone wound

A
  • if patient has had all childhood vaccines with the last dose less than 10 year ago then no need for any cover
  • otherwise give tetanus booster and add immunoglobulin if high risk wound (very contaminated, dying tissue, surgery needed)
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4
Q

what is a marjolin ulcer

A

a squamous cell carcinoma occuring at sites of chronic inflammation or previous injury

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5
Q

what are the features of acute angle closure glaucoma

A

severe pain, decreased visual acuity, semi-dilated pupil, hazy cornea

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6
Q

management of aspirin overdose within 1 hour

A

activated charcoal

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7
Q

which tumour marker is associated with hepatocellular carcinoma?

A

serum alpha fetoprotein

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8
Q

what clinical sign can often be found in patients with obstructive sleep apnoea?

A

hypertension

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9
Q

after how long do seizures typically occur in alcohol withdrawl?

A

24-48hrs (peak at 36hrs)

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10
Q

when does delirium tremens usually occur in alcohol withdrawl?

A

48- 72hrs later

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11
Q

what is first line management of alcohol withdrawl

A

long acting benzodiazepine ie chlordiazepoxide or diazepam

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12
Q

what are the causes of hyponatraemia in a patient who is euvolemic?

A

SIADH, hypothyroidism

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13
Q

what are the causes of hyponatraemia in a patient who is hypovolemic?

A

diuretics, addisons, renal failure

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14
Q

what is the management of infectious mononucleosis?

A

supportive + avoid contact sports for 4 weeks

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15
Q

what is the managment of a severe UC flare?

A

Admit for IV steroids

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16
Q

what is the management of a tympanic membrane perforation?

A
  • self resolving after 6-8 weeks + keep dry

- oral antibiotics if perforation following acute otitis media

17
Q

how do you manage acute dystonia secondary to antiphyschotics?

A

procyclidine

18
Q

what is the first line management of bilateral nasal polyps?

A

intranasal steroid spray or drops and routine referral to ENT

19
Q

what cause of gastroenteritis can precipitate lactose intolerance?

A

giardiasis

20
Q

what is the most common type of inherited colorectal cancer?

A

hereditary non-polyposis colorectal carcinoma

21
Q

what is a quick and easy bedside test to preform to confirm a nasal fluid leak is CSF

A

check for glucose

22
Q

what are the first and second line investigations for acute mesenteric ischemia?

A

1st - lactate (will be raised)

2nd - CT angio

23
Q

what electrolyte abnormality is associated with PPIs

A

hypomagnesia

24
Q

what is a useful test of exocrine function in chronic pancreatitis?

A

faecal elastase

25
Q

what cardiac arrest rhythm will tension pneumothorax cause

A

PEA

26
Q

what are the features of horner’s sydrome?

A
  • ptosis
  • miosis
  • anhidrosis (no sweating to one side of face)
27
Q

what is the management of familial hypercholestrolaemia?

A

high dose statin, management from lipid clinic, test all primary relatives (children from age 10) `

28
Q

which vaccines are live attenuated

A
  • BCG
  • MMR
  • intranasal influenxa
  • oral rotavirus
  • oral polio
  • yellow fever
  • oral typhoid
29
Q

what is the cause of kaposi’s sarcoma?

A

HHV-8 (herpes type 8)

30
Q

how does kaposi’s sarcoma present

A

purple bullae type rash on skin and mucosa

haemoptysis and pleural effusion

31
Q

what disease is associated with Kaposi’s sarcoma?

A

HIV

32
Q

what is the management of Kaposi’s sarcoma?

A

radiotherapy and resection

33
Q

how does central cord syndrome present?

A

upper limb weakness (corticospinal) and loss of upper limb pain and temperature (spinothalamic)

cape like pattern

34
Q

what are the common causes of central cord syndrome?

A

trauma (hyperextension cervical injury), tumours of spinal cord, syringohydromyelgia

35
Q

how does anterior cord syndrome present?

A

upper and lower limb weakness (corticospinal) and loss of upper and lower limb pain and temperature (spinothalamic) below level of issue

36
Q

what are the common causes of anterior cord syndrome?

A

anterior spinal artery ischemia

37
Q

how does brown-sequard syndrome present?

A

ipsilateral loss of motor + fine touch and vibration (dorsal column sensory loss) and contralateral loss of pain and temperature (spinothalamic)

38
Q

what is the common cause of brown-sequard syndrome?

A

stab injuries