Respiratory Flashcards
What is the treatment for asthma?
- SABA
- SABA + ICS
- SABA + ICS+ LABA
- LTRA
what is the treatment for COPD?
- SABA (+/- ICS)
- LABA + LAMA OR LABA + ICS
- LABA + LAMA + ICS
fine end inspiratory crackles
pulmonary fibrosis
what things cause upper zone fibrosis?
C - coal workers lung H - histiocytosis A - ankylosing spondylosis R - radiation T - TB S - sarcoidosis/silicosis
what things cause lower lobe fibrosis?
- interstitial lung disease
- asbestosis
- connective tissue disorder
- drug induced
what are side effects of the the 4 TB drugs?
Rifampicin - orange secretions
Ethambutol - eye issues
Pyramidazole - gout and hepatitis
Isoniazid - liver issues and peripheral neuropathy
what is the management of community acquired pneumonia?
mild (0-2) = oral amoxicillin 5 days
severe (3+) = IV co-amoxiclav and doxycycline
what is the managment of hospital acquired pneumonia?
non severe = amoxicillin 5 days
severe = IV amox and gent 7 days
what is the most common organism in CAP
h influenzae
what is the most common organism in HAP
pneumococcus, h influenzae
what syndromes are associated with small cell lung cancer
ACTH secreting
lambert eaton myasthenia
what syndrome is associated with squamous cell lung cancer
hypercalcaemia
what is the management of PE
haemodynamically unstable = thrombolysis
haemodynamically stable = DOAC (3 months if provoked, 6 months if unprovoked)
what is the investigation for active and latent tuberculosis
active = sputum culture is gold standard latent = mantoux test
what is bronchiectasis
chronic dilatation of the bronchi and bronchioles due to chronic infection
what is the managment of bronchiectasis?
lung physio, antibiotics, bronchodilators (SABA)
what is the best investigation for bronchiectasis
high resolution CT
what spirometry pattern is seen on bronchiectasis
obstructive
what is the genetic mutation seen in CF
AR - cystic fibrosis transmembrane conductance regulator gene on chromosome 7
what are the key features of CF
meconium ileus, recurrent chest infections, malabsorption, liver disease
how is CF diagnosed?
day 5/7 heel prick
sweat test
what is the managment of CF
- twice daily chest physio
- high calorie diet
- avoidance of other patient with CF
- pancreatic enzyme replacement
how do you differentiate between a exudate and transudate in the context of pleural effusion
Exudate = >35g protein + high LDH (often unilateral)
Transudate = <35g protein (often billateral)
what are examples of exudative causes of pleural effusion
infection, malignancy, PE, inflammation
what are examples of transudative causes of pleural effusion
congestive cardiac failure, cirrhosis, nephrotic syndrome, CKD, coeliacs
whats the difference between primary and secondary pneumothorax
secondary is when the person has an underlying lung disease
whats the management of primary pneumothorax
- <2cm and no SOB = discharge and follow up
- >2cm/ SOB = aspirate (and if doesnt work chest drain)
whats the management of a secondary pneumothorax
- > 50y/old and >2cm/SOB = chest drain
- 1-2cm = aspirate
- <1cm = admit and O2
where is a chest drain inserted
5th intercostal space mid axillary line
where is an chest aspirate inserted
2nd intercostal space mid clavicular line
give an example of a SABA
salbutamol
give an example of a SAMA
ipratropium
Give an example of a LABA
salmeterol
Give an example of a LAMA
tiotropium
pneumonia seen in alcoholics?
klebsiella pneumonia
pneumonia seen post influenza infection
staph aureus pneumonia
what are complications of mycoplasma pneumonia?
- haemolytic anaemia and thrombocytopenia (caused by cold agglutins)
- erythema multiforme
what is the management of mycoplasma pneumonia?
doxycycline or macrolide
what test is used to differentiate between severe and life threatning asthma?
ABG
what are the criteria for life threatning asthma?
- PEFR <33%
- O2 <92%
- normal pCO2
- silent chest, cyansosis, feeble resp effort
what are the criteria for severe asthma?
- PEFR 33-50%
- cannot complete full sentence
- RR >25
- HR >110
what are the criteria for moderate asthma?
- PEFR 50-75
- normal speech
- RR <25
- HR <110
which lung cancer is associated with SIADH?
small cell lung cancer
which antibiotic is used in COPD prophylaxis?
azithromycin