dementias

Question 1

what protein is involved in Alzheimer’s dementia

Answer 1

amyloid

Question 2

what investigations would you do in Alzheimer’s

Answer 2

SPECT (shows decreased metabolism), CSF for amyloid/tau ration

Question 3

whats the management of of Alzheimer’s

Answer 3

cholinesterase inhibitors

Question 4

what monitoring do you need to do for cholinesterase inhibitors?

Answer 4

ECG as can cause long QT

Question 5

What is the presentation of parkinsons dementia

Answer 5

Parkinsons and then at least a year later get dementia symptoms
+/- visual hallucinations

Question 6

what is the management of parkinsons dementia

Answer 6

small dose levodopa

Question 7

what is the presentation of Lewy body dementia

Answer 7

parkinsons and dementia present within a year of one another

Strong visual hallucinations

Question 8

what protein is associated with lewy body dementia

Answer 8

alpha synuclein

Question 9

what investigations are carried out in Lewy body dementia

Answer 9

CSF for alpha synuclein and DaT scan