endocrine

Question 1

what is the presentation of Conn’s disease/ adrenal hyperplasia?

Answer 1

high sodium, low potassium, hypertension

Question 2

what are the investigations for Conn’s disease/ adrenal hyperplasia?

Answer 2

aldosterone/renin ratio

saline suppression test

Question 3

what is the management for Conn’s disease/ adrenal hyperplasia?

Answer 3

Conn’s = surgery

adrenal hyperplasia = spironolactone

Question 4

what is the presentation for addisons?

Answer 4

weight loss, fatigue, D+V, pigmented skin

Question 5

what is the investigation for addisons?

Answer 5

short synacthen test

Question 6

what is the management for addions?

Answer 6

hydrocortisone + fludrocortisone

Question 7

what is the presentation of congenital adrenal hyperplasia?

Answer 7

salt wasting, genital ambiguity, primary amenorrhoea

Question 8

what is the management for congenital adrenal hyperplasia?

Answer 8

replace glucocorticoids + restore fertility

Question 9

what is the investigation for congenital adrenal hyperplasia?

Answer 9

17-OH progesterone

Question 10

what pattern of urine/plasma osmolarity is seen in SIADH?

Answer 10

hyponatraemia + low serum osmolarity + concentrated urine

Question 11

what pattern of urine/plasma osmolarity is seen in diabetes insipidus?

Answer 11

hypernatremia + high serum osmolarity + decreased urine osmolarity

Question 12

what are anti-histone antibodies associated with

Answer 12

drug induced lupus