Cardiology + stroke Flashcards
how do you manage a STEMI?
- MONA
- If PCI can be delivered within 120 mins = PCI + unfractionated heparin + clopidogrel/praseguel
- If PCI cannot be delivered within 120 mins = fibrinolysis (streptokinase) + antithrombin + ticegralor
how do you manage a NSTEMI/unstable angina?
- MONA
- If immediate PCI is planned = PCI + unfractionated heparin
- If PCI not planned = fondaparinux
How do you manage a stroke?
300mg aspirin as soon as haemorrhagic stroke has been ruled out + thrombolysis (within 4.5hrs of onset of symptoms) +/- thrombectomy (within 6hrs - if large vessel stroke)
what is included for secondary prevention of stroke?
- if atherosclerosis is primary cause then continue aspirin for 2 weeks then lifelong clopidogrel + statin + hypertensive mx
- if cardioembolic is primary cause then NOAC (rivaroxaban etc) +/- hypertensive mx
How do you decide if someone with AF requires anticoagulation?
CHA2DS2VAS score.
- men = 1 or more point then anticoagulate
- women = 2 or more then anticoagulate
C = congestive heart failure (1) H = hypertension (1) A2 = Age 75 or more (2) D = diabetes (1) S2 = stroke/TIA (2) V = vascular disease (1) A = age 65-75 (1) S = sex - female (1)
what is Beck’s triad?
signs of tamponade
- raised JVP
- Hypotension
- muffled heart sounds
What are the types of aortic dissection and what is the managment of each?
Type A = ascending aorta and arch of aorta. Mx is aortic graft
Type B = descending aorta. Mx is conservative - BP control is key
pulsus paradoxicus
tamponade
drop in systolic BP with inspiration
what murmur is associated with dilated cardiomyopathy
mitral regurgitation
what murmur is strongly associated with rheumatic fever
mitral stenosis
describe the inheritance of hypertrophic cardiomyopathy
AD but 50% are sporadic
what is the investigation of choice for cardiomyopathy
echo
what is rheumatic fever and how does it present
illness that presents 2-4 weeks post group A beta haemolytic strep infection (usually pharyngitis)
Symptoms include arthritis, pericarditis, chorea, erythmea marginatum, subcutanous nodules
how do you manage rheumatic fever
- IV benzylpenicillin then 10 days of phenoxymethylpenicillin
- Manage presentation ie NSAIDs for arthritis, steroids for heart failure
what organisms cause endocarditis?
- staph aureus most common. If acute presentation or IVDU think staph aureus
- staph epidermidis. Prosthetic valve less than 2 months ago
- strep viridans. Post dental procedure
what antibiotics should be used in endocarditis?
Native valve = amoxicillin and gentamicin
Prosthetic valve = vancomycin and gentamicin
IVDU/staph = flucloxicillin
what investigations should be done for endocarditis
3x blood cultures, echo
what investigations should be done for heart failure?
- ECG
- BNP (if not raised then unlikely to be heart failure)
- echo
- CXR
what is the management for heart failure (non acute)
- ACEi + B-blocker
- spironolactone
- loop diuretic ie furosemide, ivabridine
what is an important differential in a young patient with chest pain
myocarditis
what is the most common cause of myocarditis
viral infection - often coxsackie