Uterus Flashcards
Is emdometritis common?
No, not unless barrier to ascending infection is broken
Presentation of endometritis?
Low abdo pain and fever
Uterine tenderness
Discharge
Treatment for endometritis?
Antibiotics - cefalexin , metronidazole
What causes endometrial proliferation?
Oestrogen stimulation
What is endometrial proliferation associated with?
Heavy mean steal bleeding
Polyps
Treatment of endometrial bleeding?
Treat cause
Progestagens- mirena coil
What is pyometra?
Uterus distended by pus
Treatment of pyometra?
Drain and treat cause
What is a haematometra?
Uterus filled with blood due to outflow obstruction
Rare
Another name for fibroids?
Uterine leiomyomata
What are fibroids?
Benign smooth muscle tumours
Very common
Different locations of fibroids?
Subserosal
Submucosal
Intramurally
Pedunculated
Fibroids association?
Renal cell cancer
Presentation of fibroids?
Menorrhagia
Fertility problems
Pain
Mass
What is a carcinosarcoma?
High grade cancer with carcinomatous and sarcomatous elements
Prognosis of carcinosarcoma?
Poor
How common is endometrial stroma sarcoma?
Rare
Presentation of endometrial stroma sarcoma?
Abnormal uterine bleeding
May present as mets
In who does endometrial carcinoma occur?
50-60 year olds
There are two subgroups of endometrial carcinoma, what are they?
Endometrioid carcinoma
Serous carcinoma
Precursor for endometrioid carcinoma?
Atypical hyperplasia
Precursor for serous carcinoma?
Serious intraepthelial carcinoma
Presentation of endometrial carcinoma?
Abnormal postmenopausal bleeding
Examinations/ investigations for endometrial carcinoma?
TVS
Biopsy
Hysteroscopy
CT/ MRI to help stage
Treatment for endometrial carcinoma ?
Hysterectomy
Chemo/radiotherapy
Endometrioid carcinoma is related what?
Unopposed oestrogen
Potential mutations in Endometrioid carcinoma?
PTEN
KRAS
PIK 3CA
Potential mutation in serous carcinoma?
TP53
Which endometrial cancer is more aggressive and has worst prognosis?
Serous
