Uterus Flashcards

1
Q

Is emdometritis common?

A

No, not unless barrier to ascending infection is broken

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2
Q

Presentation of endometritis?

A

Low abdo pain and fever
Uterine tenderness
Discharge

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3
Q

Treatment for endometritis?

A

Antibiotics - cefalexin , metronidazole

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4
Q

What causes endometrial proliferation?

A

Oestrogen stimulation

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5
Q

What is endometrial proliferation associated with?

A

Heavy mean steal bleeding

Polyps

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6
Q

Treatment of endometrial bleeding?

A

Treat cause

Progestagens- mirena coil

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7
Q

What is pyometra?

A

Uterus distended by pus

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8
Q

Treatment of pyometra?

A

Drain and treat cause

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9
Q

What is a haematometra?

A

Uterus filled with blood due to outflow obstruction

Rare

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10
Q

Another name for fibroids?

A

Uterine leiomyomata

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11
Q

What are fibroids?

A

Benign smooth muscle tumours

Very common

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12
Q

Different locations of fibroids?

A

Subserosal
Submucosal
Intramurally
Pedunculated

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13
Q

Fibroids association?

A

Renal cell cancer

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14
Q

Presentation of fibroids?

A

Menorrhagia
Fertility problems
Pain
Mass

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15
Q

What is a carcinosarcoma?

A

High grade cancer with carcinomatous and sarcomatous elements

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16
Q

Prognosis of carcinosarcoma?

A

Poor

17
Q

How common is endometrial stroma sarcoma?

A

Rare

18
Q

Presentation of endometrial stroma sarcoma?

A

Abnormal uterine bleeding

May present as mets

19
Q

In who does endometrial carcinoma occur?

A

50-60 year olds

20
Q

There are two subgroups of endometrial carcinoma, what are they?

A

Endometrioid carcinoma

Serous carcinoma

21
Q

Precursor for endometrioid carcinoma?

A

Atypical hyperplasia

22
Q

Precursor for serous carcinoma?

A

Serious intraepthelial carcinoma

23
Q

Presentation of endometrial carcinoma?

A

Abnormal postmenopausal bleeding

24
Q

Examinations/ investigations for endometrial carcinoma?

A

TVS
Biopsy
Hysteroscopy
CT/ MRI to help stage

25
Q

Treatment for endometrial carcinoma ?

A

Hysterectomy

Chemo/radiotherapy

26
Q

Endometrioid carcinoma is related what?

A

Unopposed oestrogen

27
Q

Potential mutations in Endometrioid carcinoma?

A

PTEN
KRAS
PIK 3CA

28
Q

Potential mutation in serous carcinoma?

A

TP53

29
Q

Which endometrial cancer is more aggressive and has worst prognosis?

A

Serous