Uterus Flashcards

1
Q

Is emdometritis common?

A

No, not unless barrier to ascending infection is broken

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2
Q

Presentation of endometritis?

A

Low abdo pain and fever
Uterine tenderness
Discharge

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3
Q

Treatment for endometritis?

A

Antibiotics - cefalexin , metronidazole

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4
Q

What causes endometrial proliferation?

A

Oestrogen stimulation

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5
Q

What is endometrial proliferation associated with?

A

Heavy mean steal bleeding

Polyps

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6
Q

Treatment of endometrial bleeding?

A

Treat cause

Progestagens- mirena coil

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7
Q

What is pyometra?

A

Uterus distended by pus

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8
Q

Treatment of pyometra?

A

Drain and treat cause

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9
Q

What is a haematometra?

A

Uterus filled with blood due to outflow obstruction

Rare

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10
Q

Another name for fibroids?

A

Uterine leiomyomata

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11
Q

What are fibroids?

A

Benign smooth muscle tumours

Very common

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12
Q

Different locations of fibroids?

A

Subserosal
Submucosal
Intramurally
Pedunculated

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13
Q

Fibroids association?

A

Renal cell cancer

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14
Q

Presentation of fibroids?

A

Menorrhagia
Fertility problems
Pain
Mass

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15
Q

What is a carcinosarcoma?

A

High grade cancer with carcinomatous and sarcomatous elements

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16
Q

Prognosis of carcinosarcoma?

17
Q

How common is endometrial stroma sarcoma?

18
Q

Presentation of endometrial stroma sarcoma?

A

Abnormal uterine bleeding

May present as mets

19
Q

In who does endometrial carcinoma occur?

A

50-60 year olds

20
Q

There are two subgroups of endometrial carcinoma, what are they?

A

Endometrioid carcinoma

Serous carcinoma

21
Q

Precursor for endometrioid carcinoma?

A

Atypical hyperplasia

22
Q

Precursor for serous carcinoma?

A

Serious intraepthelial carcinoma

23
Q

Presentation of endometrial carcinoma?

A

Abnormal postmenopausal bleeding

24
Q

Examinations/ investigations for endometrial carcinoma?

A

TVS
Biopsy
Hysteroscopy
CT/ MRI to help stage

25
Treatment for endometrial carcinoma ?
Hysterectomy | Chemo/radiotherapy
26
Endometrioid carcinoma is related what?
Unopposed oestrogen
27
Potential mutations in Endometrioid carcinoma?
PTEN KRAS PIK 3CA
28
Potential mutation in serous carcinoma?
TP53
29
Which endometrial cancer is more aggressive and has worst prognosis?
Serous