Medical Complications Flashcards
What hypertensive disorders exist in pregnancy?
Chronic (essential ) hypertension
Gestational hypertension
Pre-eclampsia
What is gestational hypertension?
New hypertension after 20weeks gestation
What is pre-eclampsia?
New hypertension after 20 weeks and significant proteinuria
What other systems does hypertension in preganancy affect?
Renal
Liver
Placenta
Hypertensive Effects on renal disease?
Decrease GFR Proteinuria Increased serum Uric acid Increased creatinine/ potassium/ urea Oliguria Acute renal failure -> acute tubular necrosis , renal cortical necrosis
Hypertensive effects on liver disease?
Epigastric / RUQ pain
Abnormal liver enzymes
Hepatic capsule rupture
HELLP syndrome
What is HELLP syndrome?
Haemolysis
Elevated liver enzymes
Low platelets
Placental disease due to hypertension?
IUGR
Placental abruption
Intrauterine death
Investigations for hypertension?
U&Es Serum urate LFTs FBC Coagulation screen CTG USS
Hypertensive management?
BP monitoring
Meds- labetolol, methyldopa, nifedipine
What hypertensive medications are not ok in pregnancy?
ACEi
ARBs
What is the target BP for pregnancy?
Aim for <150/80-100 mmHg
What effects does pregnancy have on diabetes?
Poorer control
Deterioration of renal function
Deterioration of ophthalmic disease
What’s effects does diabetes have on pregnancy?
Miscarriage Fetal malformations - cardiac, neural tube defects, caudal regressions syndrome IUGR/ macrosomnia Unexplained IUD PET
What is the aim HbA1c in diabetes in pregnancy?
<6.0%