Urinary System Flashcards
What does it mean that the kidneys are retroperitoneal?
Located behind the parietal peritoneum
What are general functions of the urinary system?
Filter blood, removing metabolic wastes, toxins, and ions
* Regulate volume and chemical makeup of blood
* Balance water, salts, acids, and bases
The main structural and functional unit of the kidney is the ______
The nephron
A renal corpuscle is made of what?
glomerular capsule + glomerulus
List in order, from renal corpuscle to collecting duct, the parts of the nephron:
proximal convoluted tubule
loop of Henle
distal convoluted tubule
collecting tubule
collecting duct
What are some differences between a cortical and a juxtamedullary nephron?
Cortical nephrons
* Make up 85% of all nephrons
* Are located almost entirely within the cortex
* Nephron loops dip into medulla only a short distance
Juxtamedullary nephrons
* Make up 15% of nephrons
* Are called juxtamedullary because the renal corpuscle is near the cortex-medullary border
* Nephron loops dip deeply into medulla
* Long loops help produce concentrated urine
What are some differences between peritubular capillaries and the vasa recta?
Peritubular Capillaries
* Surround renal tubules
* Branch from efferent arteriole
* Designed for absorption and secretion
* Very porous
* Cortical nephrons have only peritubular capillaries
Vasa Recta
* Surround only tubules of juxtamedullary nephrons
* Branch from efferent arteriole of these nephrons
* Descend deep into the medulla of kidney
* Involved with concentrating urine
List the 3 overall steps of urine formation and indicate (generally) what occurs in each
- Filtration: Blood is filtered, filtrate is formed
- Resorption: Substances to keep in the body are returned to blood
- Secretion: Substances to be removed from the body enter into filtrate
What is the glomerular capsule made of (macroscopically)?
- Parietal layer forms outer layer of capsule
- Visceral layer surrounds capillaries
Describe the glomerulus and glomerular capsule
Glomerulus: Ball of fenestrated capillaries
Glomerulus capsule: covers glomerulus
Which blood vessel enters the glomerulus?
Afferent arteriole
What are podocytes and what do they have to do with the glomerular capsule?
The visceral layer is made of unusual, branching epithelial cells
called podocytes
Describe the structure of the filtration membrane. What kinds of substances can cross the filtration membrane?
Filtrate passes into capsule space through filtration slits
What are the general events that occur in the different regions of the renal tubule and collecting duct? Can you describe the epithelial linings of these regions?
Involved with resorption and secretion
* Na+/K+ pump (sodium resorbed, potassium secreted)
* Cuboidal cells resorb salt, vitamins, water
* Confined to renal cortex
* Made of simple cuboidal epithelium with microvilli
What is hemodialysis used for?
Procedure used to cleanse blood when kidneys arent filtrating