Upper GI structure and function Flashcards
4 lobes of liver
right and left (major)
caudate and quadrate (minor)
the entry and exit of vessels ducts and nerves is via the …… on the inferior surface
porta
what enters and exits liver
blood vessels (hepatic portal vein, artery)
lymphatic vessels
ducts (common hepatic)
nerves (hepatic nerve plexus)
common hepatic duct is joined by the cystic duct from the ….. to make the ……
gall bladder
common bile duct
the common bile duct + the pancreatic duct enter the
major duodenal papilla
sphincter of oddi
liver is covered in what tissue?
what peritoneum?
connective
visceral
portal triad
hepatic portal vein
hepatic artery
hepatic duct
portal triads are located at each corner of
hexagonal lobule
central veins at the centre of each lobule are HEPATIC veins that drain into the
inferior vena cava
hepatic cords are composed of
hepatocytes
functional cells of the liver
spaces between hepatic cords
hepatic sinusoids
role of the liver
production and secretion of bile
most predominant bile pigment
bilirubin
bilirubin is extracted from blood by …. and secreted into bile
hepatocytes
Bilirubin modified by bacterial enzymes gives brown pigments and therefore
brown faeces
Reabsorbed bilirubin is yellow therefore
yellow urine
bile acids are synthesised in the liver from
cholesterol
before secretion, bile acids are conjugated with glycine or taurine to make
bile salts
gall bladder secretes into the
cystic duct which secretes into the bile duct
what control bile secretion?
sphincter of oddi
sphincter of oddi controls release of ….. and ….. into the duodenum
bile and pancreatic juice
fat in the duodenum stimulates the release of what?
CCK
CCK allows for (2)
sphincter of oddi relaxation
gall bladder contraction
Discharge of bile into duodenum allows for
fat solubilisation
all functions of secretin (5)
decreases gastric acid secretion
decreases gastric emptying
increases duodenal bicarbonate secretion
increases pancreatic bicarbonate secretion
increases bile duct bicarbonate secretion
all function of CCK (4)
reduces gastric emptying
increases pancreatic enzymes secretion
gallbladder contraction
relaxation of the sphincter of oddi