Colorectal cancer Flashcards

1
Q

risk factors for colorectal cancer

A

diet

male

lack of exercise

diabetes

obesity

smoking

age

previous adenoma

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2
Q

95% of all colorectal cancers are

A

adenocarcinomas

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3
Q

1% of colorectal cancers are a direct result of

A

IBD

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4
Q

the majority of colorectal cancer arise from…

A

pre -existing polyps

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5
Q

2 main histological types of polyp

A

tubular

villous

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6
Q

adenomas are ….. in origin

A

epithelial

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7
Q

Colorectal cancer presentation

A

rectal bleeding

altered bowel movements

iron deficiency anaemia

palpable rectal or right lower abdominal mass

colonic obstruction

weight loss/anorexia

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8
Q

colorectal cancer investigation

A

colonoscopy (biopsy)

polypectomy

radiology (barium enema)

CT colonography

MRI and PET scan can be used to determine staging

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9
Q

colorectal cancer treatment

A

surgery

laparotomy

stoma formation (colostomy)

chemo and radiotherapy

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10
Q

laparotomy

A

a surgical incision into the abdominal cavity, for diagnosis or in preparation for major surgery

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11
Q

radiotherapy is used in ……. cancer only

A

rectal

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12
Q

2 methods of palliative care for advanced colorectal cancer

A

chemotherapy

colonic stenting to prevent colonic obstruction

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13
Q

5 tests for population screening of colorectal cancer

A

colonoscopy

CT colonography

faecal occult blood test (FOBT)

faecal immunochemical test (FIT)

flexible sigmoidoscopy

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14
Q

what method of screening does the Scottish bowel screening programme use

A

FOBT

faecal occult blood test

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15
Q

3 heritable conditions that can lead to colorectal cancers

A

FAP (familial adenomatous polyposis)

HNPCC (hereditary non-polyposis colorectal cancer)

IBD

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16
Q

FAP

A

familial adenomatous polyposis

17
Q

FAP is an autosomal…

A

dominant condition

18
Q

what kind of chemoprevention is used in FAP?

A

NSAIDs

19
Q

HNPCC

A

hereditary non-polyposis colorectal cancer

20
Q

HNPCC is an autosomal….

A

dominant condition