Alcohol related liver disease

Question 1

conditions that can arise in response to alcohols affects on the liver

Answer 1

encephalopathy

spontaneous bacterial peritonitis

alcoholic hepatits

fatty liver disease

Question 2

steatohepatitis

Answer 2

fatty liver with inflammation

neutrophil infiltration

fibrosis, cirrhosis

Question 3

CAGE

to stop drinking

Answer 3

have you ever felt the need to CUT down?

have you been ANNOYED by criticism of your drinking?

have you felt GUILTY about your drinking?

do you need an EYEOPENER?

Question 4

physical signs of chronic liver disease

Answer 4

spider naevi

palmar erythema

gynaecomastia

loss of axillary and pubic hair

ascites

Question 5

alcohol and the liver - conditions include

Answer 5

chronic liver disease

jaundice

muscle wasting

Question 6

causes of Hepatic Encephalopathy

Answer 6

infection

drugs

constipation

GI bleed

electrolyte disturbance

Question 7

when diagnosing Hepatic Encephalopathy you must first exclude:

Answer 7

infection

hypoglycaemia

intra cranial bleed

Question 8

Hepatic Encephalopathy treatment

Answer 8

bowel clear out, enemas

antibiotics

supportive (nasogastric tube etc)

Question 9

Spontaneous bacterial peritonitis presents as

Answer 9

abdominal pain

fever, riggers

renal impairment

signs of sepsis, tachycardia, temperature

Question 10

Spontaneous bacterial peritonitis - after the ascitic tap (draining of fluid) is performed - what tests do you do on it?

Answer 10

fluid protein and glucose levels

cultures

white cell content

Question 11

Spontaneous bacterial peritonitis treatment

Answer 11

IV antibiotics

ascitic fluid drainage (tap)

IV albumin infusion

Question 12

alcoholic hepatitis presents as

Answer 12

jaundice

encephalopathy

infection commonly

decompensated hepatic function

Question 13

alcoholic hepatitis diagnosis

Answer 13

raised bibrubin

raised GGT

alcohol history

Question 14

alcoholic hepatitis prognosis

Answer 14

40% mortality

Question 15

alcoholic hepatitis treatment

Answer 15

supportive

treat infection

treat encephalopathy

treat alcohol withdrawal

protect against GI bleeding

Question 16

Alcoholic hep score

Answer 16

glasgow alcoholic hepatitis score of less than 9

then would treat with steroids since this is a very severe case

Question 17

100% of patients with alcoholic hepatitis are

Answer 17

malnourished

Question 18

NASH

Answer 18

non alcoholic steatohepatitis

Question 19

fatty liver causes

Answer 19

obesity

diabetes

hypercholesterolaemia

alcohol

Question 20

Steatohepatitis is fatty liver PLUS ???

Answer 20

inflammation

Question 21

Steatohepatitis symptoms

Answer 21

asymptomatic

Question 22

tests for Steatohepatitis show

Answer 22

raised alanine amino transferase

fatty liver

(liver biopsy)

Question 23

treatment for Steatohepatitis

Answer 23

weight loss

exercise

Question 24

2 main treatments of alcoholic hepatitis may include

Answer 24

steroids and nutrition

Question 25

Steatohepatitis can often cause ……..

Answer 25

cirrhosis