alimentary tract pathology Flashcards
is the small bowel intraperitoneal?
NO
retroperitoneal
is the rectum retroperitoneal?
no
extraperitoneal
small bowel histology 3 cell types
goblet cells
columnar absorptive cells
endocrine cells
does the small bowel have crypts?
yes
large bowel histology is flat therefore there are no ……. they have ……
villi
crypts
both the small and large bowel peristalsis is mediated by intrinsic (…………) and extrinsic (………) neural control
myenteric plexus
autonomic innervation
myenteric plexus (or Auerbach plexus) is found
between the inner circular and outer longitudinal layers of the muscularis propria
meissener’s plexus is found at the
base of the submucosa
types of inflammatory bowel disease
ulcerative colitis
chrons disease
ischaemic colitis
radiation colitis
appendicitis
aetiology of IBD is the strong immune response to
normal flora with defects in the epithelial barrier function in genetically susceptible individuals
Chrons disease is a gene mutations on which gene?
NOD2
HLA associations in?
ulcerative colitis
Ulcerative colitis pathology
large bowel ONLY
continuous pattern of inflammation
pseudoplyps
ulceration
chrons disease pathology
granular seroa (dull grey)
mesentery is thickened
narrowing of lumen
sharp demarcation of disease segments from adjacent normal tissue
chrons histology
cryptitis and crypt abcesses
architectural distrotion
transmural inflammation
NON-CASEATING GRANULOMAS
fibrosis