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Year 2 - Alimentary System > Gastric Secretion > Flashcards

Gastric Secretion Flashcards

1
Q

3 types of cells in gastric glands

A

mucous neck cells

cheif cells

parietal cells

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2
Q

chief cells in stomach produce

A

pepsinogens

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3
Q

mucous neck cells produce

A

mucous

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4
Q

parietal cell in stomach produce

A

HCl

intrinsic factor

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5
Q

gastric acid secretion is controlled by three mechanisms

A

neurocrine (vagus reflexes)

endocrine (gastrin)

paracrine (histamine)

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6
Q

mechanisms that inhibit gastric acid secretion

A

stopping eating

reduced pH

acid in the duodenum

fat in the duodenum

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7
Q

enterogastrones

A

hormones released from gland cells in duodenal mucosa

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8
Q

enterogastrones are hormones such as

A

secretin, CCK, GIF

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9
Q

enterogastrones are released in response to

A

acid, hypertonic solutions, fatty acids or monoglycerides in duodenum

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10
Q

Enterogastrones act collectively to (2)

A

inhibit gastric secretion

reduce gastric emptying

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11
Q

pepsinogen is secreted by

A

chief cells

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12
Q

gastric mucus has a …….. role

A

cytoprotective

protects the musical surface from mechanical injury

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13
Q

GIF

A

gastric intrinsic factor

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14
Q

intrinsic factor

GIF

A

a glycoprotein produced by the parietal cells of the stomach

necessary for the absorption of vitamin B12 later on in the small intestine

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15
Q

defects in the GIF can lead to

A

anaemia

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16
Q

What do parietal cells in the stomach secrete?

A

hydrochloric acid

intrinsic factor

17
Q

what does stopping eating do to vagal activity?

A

decreases it

18
Q

What does gastrin do?

A

stimulates secretion of gastric acid (HCl) by parietal cells

19
Q

acids and fats in the duodenum do what to gastrin?

A

decrease its release

20
Q

gastric phase involves an increase in what?

and therefore a decrease in?

A

HCl

pH

21
Q

what are enterogastrones?

A

hormones released from glands in duodenal mucosa

act collectively to prevent further acid build up in duodenum

22
Q

defect in B12 can lead to

A

pernicious anaemia

Year 2 - Alimentary System (31 decks)

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