unit 11 (lymphatic) Flashcards
lymph
-runs alongside veins
-excess tissue fluid
-edema if fluid isn’t picked up
-one way system from capillary bed to lymph nodes to venous return system to blood (only toward heart)
lymph nodes
filter lymph before it’s returned to blood
spleen
-forms blood cells in fetus
-acts as blood reservoir
-filters and cleans, lymphocyte proliferation, destroys worn out RBC
-left side of abdomen
thymus
site of training for t lymphs
-overlying heart
Peyer’s patches
macrophages capture and destroy bacteria in the intestine
-walls of small intestine
tonsils
trap and remove bacteria
-throat opening of nose, mouth, and tongue
mucosa associated lymphoid tissue
appendix; acts as a sentinel to protect respiratory and digestive tracts
innate defense (nonspecific)
protects against wide varieties of invaders
adaptive defense system (specific)
fights invaders that get past innate; highly specific resistance to disease: immunity
examples of innate
surface membrane barriers
cellular
chemical defenses
fever
surface membrane barriers
intact skin and mucous membrane; first line of defense; acidic skin secretions, sebum, mucus, gastric juices, saliva and tears
cellular
second line of defense; natural killer cells and phagocytes; fever, inflammatory response, Chemicals that kill pathogens, and fever
chemical defenses
antimicrobial proteins
fever
pyrogens and hypothalamus
major steps of inflammatory response
-redness, heat, pain, swelling
-damaged cells release chemicals
-cause: phagocytes and WBC to move into area
-prevents: spread, disposes debris and pathogens, beings repair
complement
at least 20 plasma proteins circulating in plasma; form MAC’s and produce holes in cells for water to rush in
interferon
virus infected cells secrete these; bind to membrane receptors on healthy cells to interfere with ability of viruses to multiply
how a fever protects the body
-speeds repair processes (inc in temp)
-hypothalamus regulates body temp by pyrogens
-high temps inhibit release of zinc and iron that bacteria needs
humoral immunity
antibody mediated immunity; body fluid and B cells
cellular immunity
cell mediated immunity; virus -infected cells, cancer cells, cells of foreign grafts (target these)
antigen
any substance capable of exciting immune system and provoking an immune response
hapten
incomplete antigens; not antigenic by themselves; poison ivy, animal dander, detergents, hair dyes, and cosmetics
b lymphocytes
produce antibodies and oversee humoral immunity; bone marrow; can bind to specific antigen and make copies of themselves