undertopics until p- 50 Flashcards
Foetopathy of swine caused by parvoviruses (smedi) aetiology
PPV 1 - porcine parvovirus
Canine enteritis caused by parvovirus aetiology/types
CPV 1 - non pathogenic original virus of dogs
CPV 2 - Canine Protoparvovirus
Feline Panleukopenia aetiology
Parvovirus
Parvoviral diseases of the mink (2)
Mink parvovirus enteritis
Aleutian mink disease - plasmacytosis
Chicken infectious anemia aetiology
Anelloviridae family - Gyrovirus genus
Circoviral diseases of birds (3)
Psitaccine beak and feather disease
Pigeon circovirus
Goose circovirus
PMWS of swine - what does the abbreviation mean and aetiology
Porcine multisystemic wasting syndrome - caused by PCV 2
What type of porcine circoviruses exist and what do they do?
PCV 1 - non pathogenic
PCV 2 - responsible for PCV associated diseases
PCV 3 - together with PCV 2 or in asymptomatic animals
PCV 4 similar to mink circoviris
Porcine dermatitis nephropathia syndrome aetiology
PCV 2 - but may develop with other pathogens as well, e.g. Mycoplasma
Papillomavirus - which ones exist?
Bovine Papillomavirus Horse Papillomatosis Dog Papillomatosis Human papillomatosis and wild animal papillomatosis
Haemorrhagic nephritis and enteritis of geese cause
Polyomaviridae
which groups exist for adenovirus?
Mastadeno-
aviadeno-
atadeno-
siadeno, ichtadeno
Adenovirus pneumoenteritis in calves and lambs subtypes
Mastadenovirus genus : subgroup 1 - replication in bovine kidney cells
Atadenovirus genus - Subgroup 2 - replication in bovine testicle cells
Pneumovirus enteritis in lambs caused by the same
Canine infectious hepatitis and infectious laryngotracheitis agents
Infectious canine hepatitis - Rubarth disease - CAdV-1 ( Canine adeno virus type 1 )
Fox encephalitis
Infectious laryngotracheitis - kennel cough - CAdV-2
List of adenoviral diseases in poultry (7)
Chicken inclusion body hepatitis - FAdV-1 - Aviadenovirus soubgroup
Hydropericardium syndrome in geese FadV-4 Aviadenovirus
Turkey haemorrhagic enteritis - Siadenovirus genus
Marble spleen disease - in pheasants
Splenomegaly
Egg drop syndrome - Atadenovirus genus
Egg drop syndrome in goose
Infectious Bovine Rhinotracheitis aetiology
Alphaherpesvirinae: BHV-1 and BHV-5 (bovine herpesvirus)
Infectious Bovine Rhinotracheitis Main symptoms? + importance
Abortion in cows, Encephalitis in calves under 5 months, Respiratory symptoms
NOTIFIABLE
Bovine Herpesmammilitis? the occurence (continents) and the aetiology!
mainly in Africa, Australia and USA, rare in Europe
Alphaherpesvirinae: BHV-2
Malignant Catarrhal Fever Aetiology and occurence
Gammaherpesvirinae: Ovine Herpesvirus-2 (OHV 2), Alcephaline Herpesvirus-1 (AIHV-1)
in Africa: Wilderbeest associated malignant catarrhal fever, outside of africa sheep associated malignant catarrhal fever
Aujezkys disease - Which animals does it effect and what is the causative agent? + Importance
Swine is the reservoir, but Mammal and bird species also susceptible: mainly lethal encephalitis; cattle, sheep, horse, carnivores
SuHV-1 Suid Herpesvirus-1 -> antigenic relationship with BHV-1
NOTIFIABLE DISEASE
Inclusion Body Rhinitis of Swine - aetiology and whats its importance?
Suid Herpesvirus - 2 : SHV 2 Betaherpesvirinae
it is very rare that it causes clinical signs, it has no economic significance however in piglets under 3 weeks it can reach up to 25% mortality
Equine Rhinopneumonitis - Aetiology and importance?
Virus: Alphaherpesvirinae, Varicellovirus,
Equid Herpesvirus 1: Respiratory disease, abortion, CNS
Equid Herpesvirus 4: respiratory adaptation, (abortion)
Notifiable Disease!!
List of Herpesvirus Families and their mechanism of action
Alphaherpesvirus: replicate and spead rapidly, destroying host cells and establishing latent infections
Betaherpesvirus: replicate and spread slowly, causing cells to enlarge (Cytomegalovirus) - latent in secretory glands and lymphoreticular cells
Gammaherpesvirus: infect T or B Lymphocytes, latent infection in these cells
What is typical for herpesvirus in microscopic exam?
Intranuclear Inclusion Bodies (they replicate in the nucleus)
Coital Exanthema of Horses - Aetiology
Equid Herpesvirus 3 - Alphaherpesvirinae
Causative Agents of Further Herpes viral diseases of Horses + signs
EHV-2 and EHV-5 infection of Horses -> Gammaherpesvirinae
widespread, fever, mild resp signs
keratoconjuctivity
rh. equi colonisation on mucosa - pneumonia
2 -> keratoconjunctivitis + respiratory disease in young foals
the symptoms are often unnoticed
no symptoms in adult animals
EHV 5 may play a role in the equine multinodular pulmonary fibrosis
Canine Herpesviral Disease? causative agent
Canid Herpesvirus 1 (CaHV 1) Alphaherpesvirinae
Key points of Herpesvirus
Key points
Enveloped DNAviruses with icosahedral symmetry
Replicate in the nucleus
Labile in the environment
Three subfamilies of veterinary importance:
Alphaherpesvirinae, Betaherpesvirinae,
Gammaherpesvirinae
Cause diseases of the respiratory, reproductive and
nervous systems; may cause cell transformation in
some species
Latency is a common outcome of infection with
these viruses
Papillomavirus Key Points
Key points
- Non-enveloped, double-stranded DNA viruses
- Icosahedral symmetry
Contains one genus, Papillomavirus:
-Have not been cultured in vitro
–Cause papillomas and fibropapillomas in domestic animals
-Malignant transformation of alimentary and
urinary tract papillomas may occur in cattle
ingesting bracken fern
-Bovine papillomas type 1 and 2 are aetiologically involved in equine sarcoids
Parvovirus Key points
Key points
Small, non-enveloped, single-stranded DNA
viruses
- Icosahedral symmetry
Replicate in the nucleus, form intranuclear
inclusion bodies
Require rapidly-dividing cells for replication
Stable in the environment
Resistant to heat, solvents, disinfectants and pH
changes
Genus Parvovirus:
-Many have haemagglutinating activity
-Shed in large numbers in faeces
-Enteric and systemic diseases in dogs and cats
-Reproductive failure, SMEDI syndrome, in pigs
Adenovirus Key Points
Key points
Non-enveloped, double-stranded DNA viruses,
Icosahedral symmetry
Replicate in nuclei, forming intranuclear inclusion
bodies
Moderately stable in the environment
Two genera:
-Aviadenovirus, avian adenoviruses
-Mastadenovirus, mammalian adenoviruses
Systemic and Respiratory diseases in dogs
Systemic diseases in Poultry
Circovirus Key Points
Small, non-enveloped single-stranded DNA viruses
with icosahedral symmetry
Replicate in the nucleus of dividing cells
Stable in the environment
Circoviruses cause infections in chickens, pigs and
plants
Feline Herpesviral disease Aetiology
FeHV-1 (Alphaherpesvirinae)
Infectious Laryngotracheitis of Chicken Aetiology
GaH-1 Gallid Herpesvirus 1, Alphaherpesvirinae, Iltovirus
Mareks disease aetiology
Gallid Herpesvirus 2 & 3 Alphaherpesvirinae, Mardivirus
GaHV2: Mareks disease virus serotype 1 causes Mareks disease
Duck Plague Aetiology
AnHV-1 unassigned herpesvirus (genetically unique)
Anatid
Pigeon Herpes Aetiology
CoHV-1
colombid
Age of pigs susceptible to SMEDI
to 30 days embryo: death, resorption 30-70d: death of fetus, mummification from 70d: weak + mummified fetus, myoclonia congenita adults: respiratory disease rare neonates: systemic disease
Age of dogs susceptible to Parvo
3-8weeks: sudden death, myocardial damage, high motality
above 8 weeks: enteritis
