Ultraviolet Phototherapy

Question 1

Applying any form of light to the skin is analogous to applying _____ to the skin

Answer 1

energy

Question 2

UV light is part of the electromagnetic spectrum; it is _____

Answer 2

invisible

Question 3

There is an _______ relationship between wavelength and energy

Answer 3

inverse

Question 4

Does UV have a low or high photon energy? Low or high wavelength?

Answer 4

high photon energy; low wavelength

Question 5

UVB wavelength ?

Answer 5

290-320 nm

Question 6

UVA wavelength?

Answer 6

320-400 nm

Question 7

Visible light wavelength?

Answer 7

400-750 nm

Question 8

UVB is _____ times more potent than UVA in terms of biological effect. Why (2 reasons)?

Answer 8

100;

1. UVB more efficiently absorbed by the skin
2. UVB has more photon energy than UVA

Question 9

UVC light does not reach the earth surface because of the _______

Answer 9

atmosphere

Question 10

What are the 5 acute effects of UV light on the skin?

Answer 10

1. vitamin D synthesis
2. epidermal hyperproliferation
3. hyperpigmentation
4. sunburn
5. immunosuppression

Question 11

What are 3 chronic effects of UV light on the skin?

Answer 11

1. photoaging
2. immunosuppression
3. skin cancer

Question 12

How does UV light cause skin cancer?

Answer 12

via

1. DNA damage
2. chronic immunosuppression

Question 13

Technically, what is the only beneficial thing that UV light does for your body?

Answer 13

synthesize Vit D

Question 14

________ is a defense mechanism and a response to injury

Answer 14

hyperpigmentation

Question 15

The mechanisms of action for the therapeutic use of UV light in skin disease are directly related to the known_____ effects of UV light on the skin

Answer 15

acute

Question 16

UV__ is generally known for burning, and UV__ predominantly causes photoaging

Answer 16

B;A

Question 17

UVB, not UVA, contributes to skin cancer (T/F).

Answer 17

FALSE - both contribute

Question 18

_______ = with repeated exposures to UV, the actor response of the skin changes

Answer 18

photoadaptation

Question 19

What two mechanisms are photo adaptation due to?

Answer 19

1. increased melanization of the skin

2. epidermal hyper proliferation

Question 20

In general, for significant improvement, UV therapy is usually give __-__ times per week, and __-__ session in total

Answer 20

2-3; 25-50

Question 21

The therapeutic dose of UV light is normally (lower/higher) than the does that will cause an acute sunburn

Answer 21

higher

Question 22

________ allows the therapist to start with a low dose that will not cause a sunburn, and then gradually increase the UV over successive exposures in order to achieve the therapeutic dose

Answer 22

photoadaptation

Question 23

How do you measure UVB light?

Answer 23

time x intensity = fluence

Question 24

What are the 3 ways to determine the starting dose?

Answer 24

1. MED testing
2. skin typing
3. empiric

Question 25

_____ = actual light energy dose delivered to the skin

Answer 25

fluence

Question 26

_____ = lowest dose of light hat will cause redness of the skin

Answer 26

minimal erythema dose (MED)

Question 27

With MED testing the pt is exposed to small doses of UV and then the skin is checked ___ hours later for erythema

Answer 27

24

Question 28

What is skin typing ? What is it based on?

Answer 28

tan/burn history; Fitzpatrick skin typing

Question 29

What are the 6 fitzpatrick skin typing ?

Answer 29

1. burns easily, rarely tans 2. burns easily, sometimes tans 3. sometimes burns, easily tans 4. rarely burns, tans easily 5. darker skin 6. very dark skin

Question 30

______ way = every starts with the same dose

Answer 30

empiric way (BAD)

Question 31

UV light dose = start at ___ % MED if using this method, and then increase by __-__% over the previous dose treatment as tolerated

Answer 31

70; 5-10

Question 32

____ = most commonly used form of phototherapy in clinics

Answer 32

UVB

Question 33

Broad band is more effective than narrow band UVB, but he exposure times are longer (T/F)

Answer 33

FALSE; other way around

Question 34

What are 6 conditions amendable to UV therapy ?

Answer 34

1. Psoriasis 2. Eczema 3. Vitiligo 4. Pruritus secondary to renal or liver disease 5. photodermatoses 6. cutaneous lymphoma

Question 35

What is the most common indication for phototherapy ?

Answer 35

psoriasis

Question 36

Why is phototherapy effective in treatment of psoriasis?

Answer 36

immunosuppressive effects on overactive T cells in the skin that drive the inflammation and epidermal hyperproliferaion

Question 37

How is phototherapy an effective treatment for eczema?

Answer 37

like proriasis; immunosuppressive to activated T cells that cause pruritis and inflammation

Question 38

What are 2 ways that phototherapy is effective when treating vitiligo?

Answer 38

1. stimulate melanocytes | 2. suppress autoimmune reactions

Question 39

_____ band UVB or _____ required to treat vitiligo

Answer 39

narrow; PUVA

Question 40

Is broad band UVB effective in treating vitiligo?

Answer 40

no

Question 41

How many treatment sessions are required to treat vitiligo?

Answer 41

100-200

Question 42

UVB is effective in decreasing the _______ in pts with advanced kidney or liver failure

Answer 42

pruritus

Question 43

Some pt's with photodermatoses who are immunologically sensitive to light can be "_______" by using repeated low doses of UV light

Answer 43

desensitized

Question 44

CI's to UV phototherapy ?

Answer 44

1. skin cancer 2. connective tissue disease 3. photosensitivity