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PHTH 545 > Ultraviolet Phototherapy > Flashcards

Ultraviolet Phototherapy Flashcards

1
Q

Applying any form of light to the skin is analogous to applying _____ to the skin

A

energy

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2
Q

UV light is part of the electromagnetic spectrum; it is _____

A

invisible

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3
Q

There is an _______ relationship between wavelength and energy

A

inverse

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4
Q

Does UV have a low or high photon energy? Low or high wavelength?

A

high photon energy; low wavelength

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5
Q

UVB wavelength ?

A

290-320 nm

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6
Q

UVA wavelength?

A

320-400 nm

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7
Q

Visible light wavelength?

A

400-750 nm

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8
Q

UVB is _____ times more potent than UVA in terms of biological effect. Why (2 reasons)?

A

100;

  1. UVB more efficiently absorbed by the skin
  2. UVB has more photon energy than UVA
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9
Q

UVC light does not reach the earth surface because of the _______

A

atmosphere

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10
Q

What are the 5 acute effects of UV light on the skin?

A
  1. vitamin D synthesis
  2. epidermal hyperproliferation
  3. hyperpigmentation
  4. sunburn
  5. immunosuppression
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11
Q

What are 3 chronic effects of UV light on the skin?

A
  1. photoaging
  2. immunosuppression
  3. skin cancer
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12
Q

How does UV light cause skin cancer?

A

via

  1. DNA damage
  2. chronic immunosuppression
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13
Q

Technically, what is the only beneficial thing that UV light does for your body?

A

synthesize Vit D

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14
Q

________ is a defense mechanism and a response to injury

A

hyperpigmentation

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15
Q

The mechanisms of action for the therapeutic use of UV light in skin disease are directly related to the known_____ effects of UV light on the skin

A

acute

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16
Q

UV__ is generally known for burning, and UV__ predominantly causes photoaging

A

B;A

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17
Q

UVB, not UVA, contributes to skin cancer (T/F).

A

FALSE - both contribute

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18
Q

_______ = with repeated exposures to UV, the actor response of the skin changes

A

photoadaptation

19
Q

What two mechanisms are photo adaptation due to?

A
  1. increased melanization of the skin

2. epidermal hyper proliferation

20
Q

In general, for significant improvement, UV therapy is usually give __-__ times per week, and __-__ session in total

A

2-3; 25-50

21
Q

The therapeutic dose of UV light is normally (lower/higher) than the does that will cause an acute sunburn

A

higher

22
Q

________ allows the therapist to start with a low dose that will not cause a sunburn, and then gradually increase the UV over successive exposures in order to achieve the therapeutic dose

A

photoadaptation

23
Q

How do you measure UVB light?

A

time x intensity = fluence

24
Q

What are the 3 ways to determine the starting dose?

A
  1. MED testing
  2. skin typing
  3. empiric
25
Q

_____ = actual light energy dose delivered to the skin

A

fluence

26
Q

_____ = lowest dose of light hat will cause redness of the skin

A

minimal erythema dose (MED)

27
Q

With MED testing the pt is exposed to small doses of UV and then the skin is checked ___ hours later for erythema

A

24

28
Q

What is skin typing ? What is it based on?

A

tan/burn history; Fitzpatrick skin typing

29
Q

What are the 6 fitzpatrick skin typing ?

A
  1. burns easily, rarely tans
  2. burns easily, sometimes tans
  3. sometimes burns, easily tans
  4. rarely burns, tans easily
  5. darker skin
  6. very dark skin
30
Q

______ way = every starts with the same dose

A

empiric way (BAD)

31
Q

UV light dose = start at ___ % MED if using this method, and then increase by __-__% over the previous dose treatment as tolerated

A

70; 5-10

32
Q

____ = most commonly used form of phototherapy in clinics

A

UVB

33
Q

Broad band is more effective than narrow band UVB, but he exposure times are longer (T/F)

A

FALSE; other way around

34
Q

What are 6 conditions amendable to UV therapy ?

A
  1. Psoriasis
  2. Eczema
  3. Vitiligo
  4. Pruritus secondary to renal or liver disease
  5. photodermatoses
  6. cutaneous lymphoma
35
Q

What is the most common indication for phototherapy ?

A

psoriasis

36
Q

Why is phototherapy effective in treatment of psoriasis?

A

immunosuppressive effects on overactive T cells in the skin that drive the inflammation and epidermal hyperproliferaion

37
Q

How is phototherapy an effective treatment for eczema?

A

like proriasis; immunosuppressive to activated T cells that cause pruritis and inflammation

38
Q

What are 2 ways that phototherapy is effective when treating vitiligo?

A
  1. stimulate melanocytes

2. suppress autoimmune reactions

39
Q

_____ band UVB or _____ required to treat vitiligo

A

narrow; PUVA

40
Q

Is broad band UVB effective in treating vitiligo?

A

no

41
Q

How many treatment sessions are required to treat vitiligo?

A

100-200

42
Q

UVB is effective in decreasing the _______ in pts with advanced kidney or liver failure

A

pruritus

43
Q

Some pt’s with photodermatoses who are immunologically sensitive to light can be “_______” by using repeated low doses of UV light

A

desensitized

44
Q

CI’s to UV phototherapy ?

A
  1. skin cancer
  2. connective tissue disease
  3. photosensitivity

PHTH 545 (23 decks)

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