Tumors Of The Nose, Sinuses, And Nasopharynx Flashcards
What are the two benign neoplasms of the upper airways?
Nasopharyngeal angiofibroma and sinonasal papilloma
How do we characterize an angiofibroma?
Benign tumor of the nasal mucosa composed of large blood vessels and fibrous tissue.
What patient population do we find these in and what are these tumors highly associated with?
Young men, often white and red head. Associated with familial adenomatous polyposis.
2 complications of angiofibromas?
Recurrence and bleeding.
How do we characterize a sinonasal papilloma? 3 forms of sinonasal papilloma and which one is most important?
Benign neoplasm of the respiratory squamous epithelium of the nasal cavity and the paranasal sinuses.
Exophytic (most common), endophytic (invaginates rather than protrudes) and cylindrical.
What patient population most commonly is affected by sinonasal papilloma and what have they identified genetically being part of the exo and endo forms?
Middle aged males.
HPV DNA, types 6 and 11
What are the 4 malignant tumors of the upper airways?
Olfactory neuroblastoma, nut midline carcinoma, nasopharyngeal carcinoma, and extranodal NK/T cell lymphoma
How do we characterize olfactory neuroblastomas?
Tumor arising from the neuroectodermal olfactory cells in the mucosa, usually in the top of the nasal cavity.
What are the two ages of patients who usually present wit these?
Teens and middle aged.
Hallmark histo and radiograph feature of olfactory neuroblastomas?
Small round blue cell tumor.
Dumb bell shaped tumor on radiograph because it penetrates through the cribriform plate.
What is an important similarity between nasopharyngeal carcinoma and extranodal NK/T cell lymphoma?
Both are associated with Epstein Barr Virus
If you were to say, what type of carcinoma is nasopharyngeal carcinoma essentially?
Squamous
What are the three types of nasopharyngeal carcinoma?
Keratinizing, non keratinizing, and basophilic with lymphoid tissue
What are two patient populations that are affect by nasopharyngeal carcinoma?
Again adults and black kids
What is a common place of metastasis for nasopharyngeal carcinoma?
Cervical lymph nodes
