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Respiratory Medicine > Pharm - Asthma And COPD > Flashcards

Pharm - Asthma And COPD Flashcards

1
Q

What are the 4 components of asthma management?

A
  1. Routine monitoring of symptoms and lung function.
  2. Patient education
  3. Try to control triggers of the patient
  4. Medicine
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2
Q

What are the 4 categories of therapy for asthma?

A

Bronchodilators, anti inflammatory drugs, leukotrienes antagonist, and monoclonal antibody

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3
Q

What are the 3 family of drugs that are bronchodilators?

A

Beta 2 agonist, anticholinergics, methylxanthines

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4
Q

What is the one family of drug to use as an anti inflammatory?

A

Inhaled corticosteroids

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5
Q

How do bronchodilators work and what is the limitation?

A

All they do is reverse the bronchoconstriction, they do not treat the underlying inflammatory response.

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6
Q

What are three other actions of beta 2 agonist bodies dilating the airway?

A

Inhibit mast cells, reduce exudate from blood vessels, and inhibit sensory nerve activation.

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7
Q

What are the 3 indications of albuterol?

A

Acute asthma symptoms, acute bronchitis, and COPD

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8
Q

What is a drug interaction we want to stay away from with albuterol and why?

A

MAO inhibitors because they increased the risk for CV effects.

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9
Q

What is unique about terbutaline?

A

Only b2 agonist that is given subcutaneous

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10
Q

3 clinical indications for terbutaline?

A

Acute asthma, bronchitis, emphysema

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11
Q

What is an off label use of terbutaline and what are the adverse effects of this use?

A

Stopping premature labor. But a lot of heart adverse effects with the mom.

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12
Q

What is the black box warning for terbutaline?

A

Tocolysis. Premature labor contractions.

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13
Q

3 clinical indications for metaproterenol?

A

Acute asthma, bronchitis, and COPD

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14
Q

What is a serious caution/warning for using metaproterenol?

A

Can produce a serious CV effect in some patients

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15
Q

Clinical indication for pirbuterol?

A

Prevention and treatment of bronchospasm in patients 12 years and older

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16
Q

What is the caution/warning of using pirbuterol?

A

CV effect

17
Q

Clinical indication for levalbuterol?

A

Prevention and treatment of bronchospams in patients age 4 and older.

18
Q

What type of beta agonist is fomoterol?

A

Long lasting

19
Q

3 clinical indications for formoterol?

A
  1. Treatment of asthma in patients 5 or older as an add on to long term asthma control medication
  2. Prevention of exercise induce bronchospam in patients 5 years and older
  3. Maintenance treatment of bronchoconstriction in COPD patients
20
Q

What is the contraindication for a LABA like formoterol?

A

If it is not an add on it can cause asthma related deaths and asthma related hospitalizations

21
Q

What amount of time are we meaning when we say short acting beta 2 agonist and long lasting beta 2 agonist?

A

3 hours and 12 hours

22
Q

What are the clinical indications for salmeterol and what is the warning/caution with its use?

A

Same indications for salmeterol as formeterol just 4 years and older. Warning is also the same. If used alone, asthma related deaths and asthma related hospitalizations.

23
Q

What is the clinical indication for indacaterol and what is the BBW?

A

It is a LABA used to treat breathing problems caused by COPD, chronic bronchitis and emphysema.
Asthma related deaths

24
Q

What is the clinical indication for olodaterol and BBW?

A

LABA for COPD, chronic bronchitis and emphysema.

Asthma related deaths

25
Q

What are the two most common adverse effects of using beta 2 agonists?

A

Muscle tremor and palpitations.

26
Q

What is the MOA for anticholinergic drugs for asthma problems?

A

Blocks muscle contractions

27
Q

What is the clinical indication for atropine?

A

temporary Blocking severe life threading muscarinic effects

28
Q

Clinical indication for ipratropium?

A

Maintenance treatment for COPD, chronic bronchitis and emphysema.

29
Q

Clinical indication for tiotropium?

A

long term Maintenance treatment for COPD and reducing COPD exacerbation

30
Q

What is a caution/warning of tiotropium?

A

Not for acute use.

31
Q

Clinical indication for aclidinium and caution/warning?

A

Long term Maintenance treatment for COPD, chronic bronchitis and emphysema.
Not for acute use.

32
Q

What is the most widely used methylxanthine for the treatment of asthma and COPD?

A

Theophylline

33
Q

Two actions of theophylline?

A

Smooth muscle relaxation (bronchodilator) and suppression of the airway to respond to stimuli

34
Q

2 clinical indications for theophylline?

A

Asthma and COPD

35
Q

What 3 patient populations should we use extreme caution with theophylline?

A

Peptic ulcer, seizures, and cardiac arrhythmias

Respiratory Medicine (27 decks)

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