Pharm - Asthma And COPD Flashcards
What are the 4 components of asthma management?
- Routine monitoring of symptoms and lung function.
- Patient education
- Try to control triggers of the patient
- Medicine
What are the 4 categories of therapy for asthma?
Bronchodilators, anti inflammatory drugs, leukotrienes antagonist, and monoclonal antibody
What are the 3 family of drugs that are bronchodilators?
Beta 2 agonist, anticholinergics, methylxanthines
What is the one family of drug to use as an anti inflammatory?
Inhaled corticosteroids
How do bronchodilators work and what is the limitation?
All they do is reverse the bronchoconstriction, they do not treat the underlying inflammatory response.
What are three other actions of beta 2 agonist bodies dilating the airway?
Inhibit mast cells, reduce exudate from blood vessels, and inhibit sensory nerve activation.
What are the 3 indications of albuterol?
Acute asthma symptoms, acute bronchitis, and COPD
What is a drug interaction we want to stay away from with albuterol and why?
MAO inhibitors because they increased the risk for CV effects.
What is unique about terbutaline?
Only b2 agonist that is given subcutaneous
3 clinical indications for terbutaline?
Acute asthma, bronchitis, emphysema
What is an off label use of terbutaline and what are the adverse effects of this use?
Stopping premature labor. But a lot of heart adverse effects with the mom.
What is the black box warning for terbutaline?
Tocolysis. Premature labor contractions.
3 clinical indications for metaproterenol?
Acute asthma, bronchitis, and COPD
What is a serious caution/warning for using metaproterenol?
Can produce a serious CV effect in some patients
Clinical indication for pirbuterol?
Prevention and treatment of bronchospasm in patients 12 years and older
What is the caution/warning of using pirbuterol?
CV effect
Clinical indication for levalbuterol?
Prevention and treatment of bronchospams in patients age 4 and older.
What type of beta agonist is fomoterol?
Long lasting
3 clinical indications for formoterol?
- Treatment of asthma in patients 5 or older as an add on to long term asthma control medication
- Prevention of exercise induce bronchospam in patients 5 years and older
- Maintenance treatment of bronchoconstriction in COPD patients
What is the contraindication for a LABA like formoterol?
If it is not an add on it can cause asthma related deaths and asthma related hospitalizations
What amount of time are we meaning when we say short acting beta 2 agonist and long lasting beta 2 agonist?
3 hours and 12 hours
What are the clinical indications for salmeterol and what is the warning/caution with its use?
Same indications for salmeterol as formeterol just 4 years and older. Warning is also the same. If used alone, asthma related deaths and asthma related hospitalizations.
What is the clinical indication for indacaterol and what is the BBW?
It is a LABA used to treat breathing problems caused by COPD, chronic bronchitis and emphysema.
Asthma related deaths
What is the clinical indication for olodaterol and BBW?
LABA for COPD, chronic bronchitis and emphysema.
Asthma related deaths
