Tumor-Host interrelations Flashcards

1
Q

may destroy vital structures due to their location and may even be fatal if benign, for instance, MENINGIOMA OF THE BRAIN

A

tumor masses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Local Effects

A

✓ Tumor masses (meningioma of the brain)
✓ obstruction in hollow organs (intestinal adenomas)
✓ ulcerations (cause thrombosis or infarction)
✓ observed clinical problems or cause necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Systemic Effects

A

✓ cancer cachexia
✓ systemic reactions
✓ hormone production
✓ paraneoplastic syndromes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

the wasting of body mass occuring out of proportion to the mass of neoplasm may be due to general inappetence resulting from the liberation of toxic products

A

cancer cachexia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

cancer cachexia also;

A

✓ malabsorption
✓ increased metabolism
✓ chronic infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

this includes fever resulting from tissue necrosis and concomitant infection

A

systemic reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

caused by progressive blood loss from ulcerated areas, and the weakening of the body’s natural resistance due to tumors products

A

anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

some tumors retain their functional ability and secrete substances that may cause disease in the host

A

hormone production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

functioning tumors of endocrine glands such as;

A

✓ adrenal cortex and medulla
✓ parathyroid
✓ pancreatic islets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

are known to produce hormones in excess

A

pancreatic islets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

some non-endocrine tumors produce ectopic hormone inappropriate for their tissue origin. when this happen, the clinical signs and symptoms cannot be explained by the presence of the local tumor

A

paraneoplastic syndromes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Some tumors causing paraneoplastic syndromes

A

✓ B-cell neoplasia
✓ multiple myeloma
✓ lymphoma
✓ anal gland carcinoma
✓ sertoli cell tumor
✓ pulmonary neoplasm
✓ mast cell tumor
✓ pancreatic B-cell neoplasia
✓ pituitary neoplasm
✓ adrenal tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly